Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 18/20 | 0.74 |
| ▸ | POLB | P06746 | 1/20 | 0.69 |
| ▸ | MAPT | P10636 | 1/20 | 0.69 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.69 |
| ▸ | GALR3 | O60755 | 1/20 | 0.64 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.64 |
| ▸ | RAB9A | P51151 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3764536 | 0.85 | FAAH (1.00) | FAAHPOLBMAPTMAPK1GALR3 | |
| SCHEMBL3764633 | 0.85 | FAAH (1.00) | FAAHPOLBMAPTMAPK1GALR3 | |
| SCHEMBL5275554 | 0.85 | FAAH (0.77) | FAAHPOLBMAPTMAPK1GALR3 | |
| SCHEMBL3765851 | 0.85 | FAAH (0.77) | FAAHPOLBMAPTMAPK1GALR3 | |
| SCHEMBL3766339 | 0.85 | FAAH (1.00) | FAAHPOLBMAPTMAPK1GALR3 | |
| SCHEMBL4458573 | 0.84 | FAAH (0.76) | FAAHPOLBMAPTMAPK1GALR3 | |
| SCHEMBL5060772 | 0.84 | FAAH (0.76) | FAAHPOLBMAPTMAPK1GALR3 | |
| SCHEMBL1164398 | 0.83 | FAAH (1.00) | FAAH | |
| SCHEMBL13817555 | 0.83 | FAAH (1.00) | FAAHPOLBMAPTMAPK1GALR3 | |
| SCHEMBL3766101 | 0.82 | FAAH (0.76) | FAAHPOLBMAPTMAPK1GALR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7541359-B2 | N-heteroarylpiperazinyl ureas as modulators of fatty acid amide hydrolase | JANSSEN PHARMACEUTICA N.V. (BE) | 2009-06-02 | — | — | US | disclosed |