Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 1/20 | 0.35 |
| ▸ | PARP1 | P09874 | 1/20 | 0.33 |
| ▸ | HRH1 | P35367 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14579592 | 0.79 | CCR1 (0.35) | CCR1PARP1 | |
| SCHEMBL16312650 | 0.73 | CCR1 (0.33) | CCR1 | |
| SCHEMBL14579805 | 0.73 | CCR1 (0.59) | CCR1PARP1HRH1LMNA | |
| SCHEMBL14420192 | 0.67 | CCR1 (0.32) | CCR1 | |
| SCHEMBL436923 | 0.63 | CCR1 (0.59) | CCR1PARP1HRH1LMNA | |
| SCHEMBL436922 | 0.63 | CCR1 (0.59) | CCR1PARP1HRH1LMNA | |
| SCHEMBL18633833 | 0.62 | CCR1 (0.42) | CCR1HRH1LMNA | |
| SCHEMBL18895974 | 0.59 | CCR1 (0.38) | CCR1HRH1LMNA | |
| SCHEMBL9375176 | 0.58 | TBXA2R (0.64) | HRH1 | |
| SCHEMBL6859760 | 0.57 | CCR1 (0.34) | CCR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7541365-B2 | Chemokine receptor antagonists and methods of use therefor | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2009-06-02 | — | — | US | disclosed |