Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXA2R | P21731 | 7/20 | 0.64 |
| ▸ | TBXAS1 | P24557 | 3/20 | 0.63 |
| ▸ | HRH1 | P35367 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9375168 | 1.00 | TBXA2R (0.64) | TBXA2RTBXAS1HRH1 | |
| SCHEMBL9316653 | 0.89 | TBXA2R (0.66) | TBXA2RTBXAS1HRH1 | |
| SCHEMBL9047907 | 0.89 | TBXA2R (0.66) | TBXA2RTBXAS1HRH1 | |
| SCHEMBL9044687 | 0.86 | TBXA2R (0.67) | TBXA2RTBXAS1 | |
| SCHEMBL9044692 | 0.86 | TBXA2R (0.67) | TBXA2RTBXAS1 | |
| SCHEMBL9047398 | 0.86 | TBXA2R (0.67) | TBXA2RTBXAS1 | |
| SCHEMBL5056588 | 0.85 | HRH1 (0.74) | HRH1 | |
| SCHEMBL9749916 | 0.85 | HRH1 (0.74) | HRH1 | |
| SCHEMBL5056578 | 0.85 | HRH1 (0.74) | HRH1 | |
| SCHEMBL5056536 | 0.85 | HRH1 (0.74) | HRH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0312051-B1 | Tricyclic compounds | KYOWA HAKKO KOGYO KK (JP) | 1994-08-17 | — | — | EP | disclosed |
| US-5010087-A | Cardiovascular disorders | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1991-04-23 | — | — | US | disclosed |
| US-5010104-A | Antiischemic agent, cardiovascular disorders | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1991-04-23 | — | — | US | disclosed |
| US-4882351-A | CARDIOVASCULAR DISORDERS; | ROUSSEL UCLAF (FR) | 1989-11-21 | — | — | US | disclosed |
| EP-0312051-A2 | Tricyclic compounds | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1989-04-19 | — | — | EP | disclosed |