Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 14/20 | 0.55 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13824645 | 0.85 | ACHE (0.58) | ACHECA12CA1CA2CA9 | |
| SCHEMBL13824579 | 0.80 | ACHE (0.64) | ACHE | |
| SCHEMBL8591415 | 0.80 | ACHE (0.64) | ACHEEPHX2 | |
| SCHEMBL10939707 | 0.78 | ACHE (0.81) | ACHEEPHX2 | |
| SCHEMBL7569673 | 0.78 | ACHE (0.81) | ACHEEPHX2 | |
| SCHEMBL3975468 | 0.78 | ACHE (0.88) | ACHEEPHX2 | |
| SCHEMBL8589912 | 0.77 | ACHE (0.59) | ACHECA12CA1CA2CA9 | |
| SCHEMBL7785857 | 0.76 | ACHE (0.85) | ACHEEPHX2 | |
| SCHEMBL473236 | 0.76 | ACHE (0.85) | ACHEEPHX2 | |
| SCHEMBL10447924 | 0.76 | ACHE (0.85) | ACHEEPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012150866-A1 | PHOSPHORIBOSYLTRANSFERASE INHIBITORS AND USES THEREOF | INDUSTRIAL RESEARCH LIMITED (NZ) | 2012-11-08 | — | — | WO | disclosed |