Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | PAX8 | Q06710 | 2/20 | 0.44 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.44 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | XBP1 | P17861 | 1/20 | 0.44 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.44 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.44 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.41 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | RXRA | P19793 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL977465 | 0.88 | MAPT (0.55) | ALDH1A1L3MBTL1MEN1KMT2AMAPT | |
| SCHEMBL27893393 | 0.88 | L3MBTL1 (0.51) | ALDH1A1L3MBTL1MEN1KMT2AMAPT | |
| SCHEMBL22530375 | 0.82 | MRGPRX4 (0.47) | ALDH1A1L3MBTL1MEN1KMT2AMAPT | |
| SCHEMBL29434530 | 0.82 | MRGPRX4 (0.47) | ALDH1A1L3MBTL1MEN1KMT2AMAPT | |
| SCHEMBL2277550 | 0.81 | L3MBTL1 (0.45) | ALDH1A1L3MBTL1MEN1KMT2AMAPT | |
| SCHEMBL14812142 | 0.81 | MEN1 (0.48) | ALDH1A1L3MBTL1MEN1KMT2AMAPT | |
| SCHEMBL10068550 | 0.78 | MEN1 (0.46) | ALDH1A1L3MBTL1MEN1KMT2AMAPT | |
| SCHEMBL2566899 | 0.78 | MRGPRX4 (0.50) | ALDH1A1L3MBTL1MEN1KMT2AMAPT | |
| SCHEMBL25209013 | 0.76 | L3MBTL1 (0.41) | ALDH1A1L3MBTL1MEN1KMT2AMAPT | |
| SCHEMBL21268338 | 0.75 | L3MBTL1 (0.46) | ALDH1A1L3MBTL1MEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2245019-B1 | 4, 5-DIHYDRO-OXAZOL-2-YL AMINE DERIVATIVES | HOFFMANN LA ROCHE (CH) | 2012-11-14 | — | — | EP | disclosed |