Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 16/20 | 0.41 |
| ▸ | CTSD | P07339 | 8/20 | 0.41 |
| ▸ | BACE2 | Q9Y5Z0 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2283550 | 0.89 | BACE1 (0.39) | BACE1CTSDBACE2 | |
| SCHEMBL2283554 | 0.89 | BACE1 (0.39) | BACE1CTSDBACE2 | |
| SCHEMBL2279663 | 0.84 | BACE1 (0.37) | BACE1CTSD | |
| SCHEMBL2279656 | 0.84 | BACE1 (0.37) | BACE1CTSD | |
| SCHEMBL13760888 | 0.83 | BACE1 (0.45) | BACE1CTSD | |
| SCHEMBL13825459 | 0.79 | BACE1 (0.45) | BACE1CTSDBACE2 | |
| SCHEMBL13825376 | 0.79 | BACE1 (0.41) | BACE1CTSDBACE2 | |
| SCHEMBL13761170 | 0.79 | BACE1 (0.42) | BACE1CTSD | |
| SCHEMBL13825348 | 0.77 | BACE1 (0.48) | BACE1CTSDBACE2 | |
| SCHEMBL2281196 | 0.75 | BACE1 (0.45) | BACE1CTSDBACE2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2245019-B1 | 4, 5-DIHYDRO-OXAZOL-2-YL AMINE DERIVATIVES | HOFFMANN LA ROCHE (CH) | 2012-11-14 | — | — | EP | disclosed |