Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | POLH | Q9Y253 | 1/20 | 0.33 |
| ▸ | CDC25A | P30304 | 1/20 | 0.33 |
| ▸ | CDC25B | P30305 | 1/20 | 0.33 |
| ▸ | CDC25C | P30307 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13727056 | 0.81 | HTR2B (0.38) | MAPTPPARGALDH1A1 | |
| SCHEMBL13826004 | 0.81 | BCL2 (0.35) | PTPN1MAPTALDH1A1ADORA3CYP1A2 | |
| SCHEMBL13825908 | 0.81 | BCL2 (0.35) | PTPN1MAPTALDH1A1ADORA3CYP1A2 | |
| SCHEMBL13826315 | 0.77 | ALDH1A1 (0.43) | MAPTALDH1A1ADORA3CYP1A2GAA | |
| SCHEMBL13727620 | 0.75 | MAPT (0.45) | PTPN1MAPTPPARGALDH1A1ADORA3 | |
| SCHEMBL27334864 | 0.72 | ALDH1A1 (0.52) | MAPTALDH1A1ADORA3CYP1A2CYP2C9 | |
| SCHEMBL31276071 | 0.72 | ALDH1A1 (0.52) | MAPTALDH1A1ADORA3CYP1A2CYP2C9 | |
| Alcohol SCHEMBL28016616 | 0.72 | ALDH1A1 (0.53) | MAPTALDH1A1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL27934311 | 0.71 | ALDH1A1 (0.44) | MAPTALDH1A1ADORA3CYP1A2CYP2C9 | |
| SCHEMBL31398712 | 0.70 | MAPT (0.44) | MAPTALDH1A1CYP1A2CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012151525-A9 | NOVEL COMPOUNDS AS MODULATORS OF PROTEIN KINASES | RHIZEN PHARMACEUTICALS SA (CH) | 2012-12-13 | — | — | WO | disclosed |
| WO-2012151525-A1 | NOVEL COMPOUNDS AS MODULATORS OF PROTEIN KINASES | RHIZEN PHARMACEUTICALS SA (CH) | 2012-11-08 | — | — | WO | disclosed |