SCHEMBL13826367

SCHEMBL13826367

CC1C(S(=O)(=O)O)CCC1S(=O)(=O)O

nearest known ligand 0.35

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.35
LMNA P02545 1/20 0.35
CYP3A4 P08684 1/20 0.35
GABRA1 P14867 1/20 0.35
GABRG2 P18507 1/20 0.35
NFKB1 P19838 1/20 0.35
GABRB3 P28472 1/20 0.35
GABRA5 P31644 1/20 0.35
GABRA3 P34903 1/20 0.35
GABRA2 P47869 1/20 0.35
GABRA6 Q16445 1/20 0.35
GRM5 P41594 4/20 0.32
GRM1 Q13255 2/20 0.32
TDP1 Q9NUW8 1/20 0.32
FUCA1 P04066 1/20 0.31
MEN1 O00255 1/20 0.30
ALDH1A1 P00352 1/20 0.30
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19072585 1.00 TSHR (0.35) TSHRLMNACYP3A4GABRA1GABRG2
SCHEMBL11805968 0.83 GRM5 (0.31) GRM5GRM1
SCHEMBL31257847 0.81 TSHR (0.41) TSHRLMNACYP3A4GABRA1GABRG2
SCHEMBL28933991 0.73 TSHR (0.36) TSHRLMNACYP3A4GABRA1GABRG2
SCHEMBL23654698 0.72 GRM5 (0.31) GRM5GRM1
Ammonia Solution, Strong SCHEMBL27991894 0.71
SCHEMBL17351844 0.70 CA1 (0.35) TSHRLMNACYP3A4GABRA1GABRG2
SCHEMBL27769894 0.69 TSHR (0.38) TSHRLMNACYP3A4GABRA1GABRG2
SCHEMBL17319456 0.69 INPP5A (0.38) TSHRLMNACYP3A4GABRA1GABRG2
SCHEMBL11406214 0.67 GRM5 (0.31) GRM5GRM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9496502-B2 Organic ionic compounds, compositions and electronic devices MERCK PATENT GMBH (DE) 2016-11-15 US disclosed
US-9496502-B2 Organic ionic compounds, compositions and electronic devices MERCK PATENT GMBH (DE) 2016-11-15 US disclosed
US-20140249606-A1 ORGANIC IONIC COMPOUNDS, COMPOSITIONS AND ELECTRONIC DEVICES MERCK PATENT GMBH PATENTS & SCIENTIFIC INFORMATION (DE) 2014-09-04 US disclosed
US-20140249606-A1 ORGANIC IONIC COMPOUNDS, COMPOSITIONS AND ELECTRONIC DEVICES MERCK PATENT GMBH PATENTS & SCIENTIFIC INFORMATION (DE) 2014-09-04 US disclosed
WO-2012152366-A1 ORGANIC IONIC COMPOUNDS, COMPOSITIONS AND ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2012-11-15 WO disclosed