Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.49 |
| ▸ | MAPT | P10636 | 7/20 | 0.49 |
| ▸ | NPC1 | O15118 | 4/20 | 0.49 |
| ▸ | RAB9A | P51151 | 4/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | ESR1 | P03372 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.48 |
| ▸ | HPGD | P15428 | 3/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.45 |
| ▸ | HPSE | Q9Y251 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29054491 | 0.83 | ALDH1A1 (0.55) | ALDH1A1MAPTNPC1RAB9AESR1 | |
| SCHEMBL805163 | 0.83 | ALDH1A1 (0.46) | ALDH1A1MAPTNPC1RAB9APKM | |
| SCHEMBL13719298 | 0.79 | MAPT (0.45) | ALDH1A1MAPTNPC1RAB9APKM | |
| SCHEMBL282040 | 0.79 | ALDH1A1 (0.53) | ALDH1A1MAPTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL29288167 | 0.75 | HSD17B2 (0.41) | ALDH1A1MAPTNPC1RAB9APKM | |
| SCHEMBL29288168 | 0.75 | HSD17B2 (0.41) | ALDH1A1MAPTNPC1RAB9APKM | |
| SCHEMBL7977954 | 0.74 | ALDH1A1 (0.73) | ALDH1A1MAPTNPC1RAB9APKM | |
| SCHEMBL624093 | 0.74 | ALDH1A1 (0.65) | ALDH1A1MAPTNPC1RAB9APKM | |
| SCHEMBL15996807 | 0.73 | MAPT (0.50) | ALDH1A1MAPTNPC1RAB9APKM | |
| SCHEMBL6875538 | 0.72 | SLC2A1 (0.43) | ALDH1A1MAPTNPC1RAB9APKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012150369-A1 | PHOSPHODIESTERASE-7-INHIBITING HETEROCYCLIC DERIVATIVES | CONSEJO SUPERIOR DE INVESTIGACIONES CIENTÍFICAS (ES) | 2012-11-08 | — | — | WO | disclosed |