Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 7/20 | 0.45 |
| ▸ | MAPT | P10636 | 5/20 | 0.45 |
| ▸ | TOP2A | P11388 | 4/20 | 0.45 |
| ▸ | BACE1 | P56817 | 3/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.45 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.45 |
| ▸ | MAOA | P21397 | 2/20 | 0.45 |
| ▸ | MAOB | P27338 | 2/20 | 0.45 |
| ▸ | PTGES | O14684 | 2/20 | 0.45 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.45 |
| ▸ | BCHE | P06276 | 2/20 | 0.45 |
| ▸ | ACHE | P22303 | 2/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13827755 | 0.96 | APP (0.48) | APPMAPTTOP2ABACE1CYP2D6 | |
| SCHEMBL13827610 | 0.91 | BCHE (0.47) | APPMAPTTOP2ABACE1CYP2D6 | |
| SCHEMBL13827364 | 0.79 | MAPT (0.49) | APPMAPTTOP2ABACE1CYP2D6 | |
| SCHEMBL13827462 | 0.77 | APP (0.51) | APPMAPTTOP2ABACE1CYP2D6 | |
| SCHEMBL13125809 | 0.76 | TOP2A (0.59) | APPMAPTTOP2ABACE1CYP2D6 | |
| SCHEMBL13827466 | 0.74 | APP (0.53) | APPMAPTTOP2ABACE1CYP2D6 | |
| SCHEMBL15107045 | 0.73 | TOP2A (0.52) | APPMAPTTOP2ABACE1CYP2D6 | |
| SCHEMBL14219786 | 0.72 | TOP2A (0.51) | APPMAPTTOP2ABACE1CYP2D6 | |
| SCHEMBL13827293 | 0.72 | APP (0.54) | APPMAPTTOP2ABACE1CYP2D6 | |
| SCHEMBL9906246 | 0.71 | APP (0.49) | APPMAPTTOP2ABACE1CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012154564-A1 | FATTY ACID PHENOLIC DERIVATIVES AND THEIR USES | CATABASIS PHARMACEUTICALS, INC. (US) | 2012-11-15 | — | — | WO | disclosed |