Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR4 | P61073 | 2/20 | 0.50 |
| ▸ | FAAH | O00519 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | MBOAT4 | Q96T53 | 1/20 | 0.40 |
| ▸ | PIM1 | P11309 | 1/20 | 0.40 |
| ▸ | SCN9A | Q15858 | 3/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | PARP1 | P09874 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15650850 | 0.92 | PARP1 (0.47) | CXCR4FAAHKDM4ESCN9APARP1 | |
| SCHEMBL1118921 | 0.92 | KDM4E (0.49) | CXCR4KDM4EALDH1A1SCN9AHPGD | |
| SCHEMBL15651529 | 0.90 | HRH3 (0.49) | CXCR4FAAHKDM4EALDH1A1L3MBTL1 | |
| SCHEMBL15651024 | 0.89 | CXCR4 (0.69) | CXCR4KDM4EALDH1A1SCN9AHSD17B10 | |
| SCHEMBL15651016 | 0.89 | PARP1 (0.47) | CXCR4FAAHKDM4EALDH1A1NPSR1 | |
| SCHEMBL1118930 | 0.89 | HRH3 (0.47) | CXCR4KDM4EALDH1A1PARP1 | |
| SCHEMBL15652750 | 0.89 | CXCR4 (0.63) | CXCR4ALDH1A1SCN9AHSD17B10PARP1 | |
| SCHEMBL15652638 | 0.88 | KMT2A (0.55) | CXCR4FAAHKDM4EALDH1A1SCN9A | |
| SCHEMBL15652640 | 0.88 | CXCR4 (0.43) | CXCR4FAAHKDM4EALDH1A1NPSR1 | |
| SCHEMBL15652389 | 0.87 | KDM4E (0.44) | CXCR4KDM4EALDH1A1NPSR1SCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11246949-B2 | Imaging contrast agents and uses thereof | THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (US) | 2022-02-15 | — | — | US | disclosed |
| US-20140193344-A1 | IMAGING CONTRAST AGENTS AND USES THEREOF | THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK (US) | 2014-07-10 | — | — | US | disclosed |
| US-20140193344-A1 | IMAGING CONTRAST AGENTS AND USES THEREOF | THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK (US) | 2014-07-10 | — | — | US | disclosed |
| WO-2012155076-A2 | IMAGING CONTRAST AGENTS AND USES THEREOF | THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK (US) | 2012-11-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140193344-A1 | IMAGING CONTRAST AGENTS AND USES THEREOF | SLC40A1, SLC39A14, SLC39A3 | CXCR4 669/4885FAAH 2058/4885KDM4E 4649/4885 |
| US-11246949-B2 | Imaging contrast agents and uses thereof | SLC40A1, SLC39A14, SLC39A3 | CXCR4 669/4885FAAH 2058/4885KDM4E 4649/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.