SCHEMBL1383324

SCHEMBL1383324

O=C(c1ccc(Cl)cc1NS(=O)(=O)c1cccc2nccnc12)N1CCCCC1

nearest known ligand 0.83

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
CCKBR P32239 20/20 0.83

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1381855 1.00 CCKBR (0.83) CCKBR
SCHEMBL1386421 0.91 CCKBR (1.00) CCKBR
SCHEMBL1385673 0.89 CCKBR (0.71) CCKBR
SCHEMBL27636474 0.89 CCKBR (0.66) CCKBR
SCHEMBL1386273 0.89 CCKBR (0.83) CCKBR
SCHEMBL1382550 0.89 CCKBR (1.00) CCKBR
SCHEMBL1383041 0.89 CCKBR (1.00) CCKBR
SCHEMBL1381335 0.89 CCKBR (0.83) CCKBR
SCHEMBL27657450 0.89 CCKBR (0.66) CCKBR
SCHEMBL1382876 0.86 CCKBR (0.76) CCKBR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-4818110-B2 2011-11-16 JP claimed
EP-1651621-B1 2- (QUINOXALIN-5-YLSULFONYLAMINO) -BENZAMIDE COMPOUNDS AS CCK2 MODULATORS JANSSEN PHARMACEUTICA NV (BE) 2008-08-06 EP claimed
US-7947833-B2 methods that are useful in the preparation of amidophenyl-sulfonylamino-quinoxaline compounds CCK2 modulators are disclosed by sulfonylation JANSSEN PHARMACEUTICA NV (BE) 2011-05-24 US disclosed