Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK1 | P06493 | 1/20 | 0.66 |
| ▸ | CDK4 | P11802 | 1/20 | 0.66 |
| ▸ | CDK2 | P24941 | 1/20 | 0.66 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | PNP | P00491 | 1/20 | 0.41 |
| ▸ | CASP6 | P55212 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28538636 | 0.79 | CDK1 (1.00) | CDK1CDK4CDK2MEN1KMT2A | |
| SCHEMBL12652113 | 0.76 | CDK1 (0.66) | CDK1CDK4CDK2MEN1KMT2A | |
| SCHEMBL4572376 | 0.76 | CDK1 (0.66) | CDK1CDK4CDK2MEN1KMT2A | |
| SCHEMBL12820920 | 0.72 | KDM4E (0.60) | CDK1CDK4CDK2MEN1KMT2A | |
| SCHEMBL7766478 | 0.69 | CDK2 (0.42) | CDK1CDK4CDK2MEN1KMT2A | |
| SCHEMBL15907848 | 0.68 | PNP (0.41) | CDK1CDK4CDK2MEN1KMT2A | |
| SCHEMBL10780551 | 0.67 | CDK1 (0.53) | CDK1CDK4CDK2MEN1KMT2A | |
| SCHEMBL10871152 | 0.67 | — | — | |
| SCHEMBL12820938 | 0.66 | — | — | |
| SCHEMBL3180710 | 0.66 | CDK1 (0.52) | CDK1CDK4CDK2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2707487-B1 | RIBOSWITCHES | UNIV MANCHESTER (GB) | 2017-10-04 | — | — | EP | disclosed |
| US-20140213779-A1 | RIBOSWITCHES | THE UNIVERSITY OF MANCHESTER (GB) | 2014-07-31 | — | — | US | disclosed |
| WO-2012153142-A2 | RIBOSWITCHES | THE UNIVERSITY OF MANCHESTER (GB) | 2012-11-15 | — | — | WO | disclosed |