Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNP | P00491 | 2/20 | 0.41 |
| ▸ | XDH | P47989 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | CDK1 | P06493 | 1/20 | 0.37 |
| ▸ | CDK4 | P11802 | 1/20 | 0.37 |
| ▸ | CDK2 | P24941 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | THRB | P10828 | 2/20 | 0.36 |
| ▸ | MITF | O75030 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | HBB | P68871 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | QTRT1 | Q9BXR0 | 1/20 | 0.35 |
| ▸ | TYMS | P04818 | 1/20 | 0.35 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13833302 | 0.68 | CDK1 (0.66) | PNPMAPTCDK1CDK4CDK2 | |
| SCHEMBL3180710 | 0.66 | CDK1 (0.52) | PNPMAPTCDK1CDK4CDK2 | |
| SCHEMBL4570273 | 0.64 | ALDH1A1 (0.54) | PNPMAPK1MAPTCDK1CDK4 | |
| SCHEMBL9655823 | 0.63 | MAPK1 (0.48) | PNPXDHMAPK1MAPTCDK1 | |
| SCHEMBL10954474 | 0.63 | MAPK1 (0.41) | PNPXDHMAPK1MAPTCDK1 | |
| SCHEMBL10169133 | 0.63 | NPSR1 (0.66) | PNPMAPK1MAPTKMT2AMEN1 | |
| SCHEMBL9653630 | 0.63 | NPSR1 (0.49) | PNPXDHMAPK1MAPTCDK1 | |
| SCHEMBL42761 | 0.60 | KDM4E (0.53) | PNPMAPTCDK1CDK4CDK2 | |
| SCHEMBL42760 | 0.60 | PNP (0.73) | PNPMAPTKMT2AMEN1THRB | |
| SCHEMBL1271646 | 0.60 | CDK1 (0.56) | PNPMAPTCDK1CDK4CDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140213779-A1 | RIBOSWITCHES | THE UNIVERSITY OF MANCHESTER (GB) | 2014-07-31 | — | — | US | disclosed |