Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.82 |
| ▸ | POLB | P06746 | 1/20 | 0.71 |
| ▸ | DOT1L | Q8TEK3 | 3/20 | 0.70 |
| ▸ | DPP4 | P27487 | 1/20 | 0.70 |
| ▸ | MEN1 | O00255 | 1/20 | 0.70 |
| ▸ | SLC28A1 | O00337 | 1/20 | 0.70 |
| ▸ | MAP3K7 | O43318 | 1/20 | 0.70 |
| ▸ | SLC28A2 | O43868 | 1/20 | 0.70 |
| ▸ | GAPDH | P04406 | 1/20 | 0.70 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.70 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.70 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.70 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.70 |
| ▸ | STAT6 | P42226 | 1/20 | 0.70 |
| ▸ | PI4KA | P42356 | 1/20 | 0.70 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.70 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.70 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.70 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.70 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.70 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13834964 | 1.00 | ADORA3 (0.82) | ADORA3POLBDOT1LDPP4MEN1 | |
| SCHEMBL13834960 | 1.00 | ADORA3 (0.82) | ADORA3POLBDOT1LDPP4MEN1 | |
| SCHEMBL646664 | 0.90 | ADORA3 (1.00) | ADORA3POLBDOT1LDPP4MEN1 | |
| SCHEMBL30612749 | 0.90 | ADORA3 (1.00) | ADORA3POLBDOT1LDPP4MEN1 | |
| SCHEMBL646666 | 0.90 | ADORA3 (1.00) | ADORA3POLBDOT1LDPP4MEN1 | |
| SCHEMBL14263529 | 0.90 | ADORA3 (1.00) | ADORA3POLBDOT1LDPP4MEN1 | |
| SCHEMBL646665 | 0.90 | ADORA3 (1.00) | ADORA3POLBDOT1LDPP4MEN1 | |
| SCHEMBL14565267 | 0.90 | ADORA3 (1.00) | ADORA3POLBDOT1LDPP4MEN1 | |
| SCHEMBL506313 | 0.90 | DOT1L (0.81) | ADORA3DOT1LDPP4MEN1SLC28A1 | |
| SCHEMBL8332213 | 0.90 | DOT1L (0.81) | ADORA3DOT1LDPP4MEN1SLC28A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2707483-B1 | METHODS AND MATERIALS FOR NUCLEIC ACID MANIPULATION | RWTH AACHEN UNIV (DE) | 2017-10-18 | — | — | EP | disclosed |
| US-20120295311-A1 | Methods and Materials for Nucleic Acid Manipulation | BASF SE (DE) | 2012-11-22 | — | — | US | disclosed |