Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IL2 | P60568 | 11/20 | 0.54 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.48 |
| ▸ | ABCC1 | P33527 | 2/20 | 0.48 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.44 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | ABL1 | P00519 | 1/20 | 0.43 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13838505 | 0.84 | IL2 (0.53) | IL2 | |
| SCHEMBL11911923 | 0.84 | IL2 (0.65) | IL2 | |
| SCHEMBL13838385 | 0.83 | IL2 (0.54) | IL2 | |
| SCHEMBL13838427 | 0.83 | IL2 (0.46) | IL2ABCB1ABCC1ABL1 | |
| SCHEMBL13727779 | 0.83 | IL2 (0.51) | IL2ABL1 | |
| SCHEMBL13729449 | 0.83 | IL2 (0.51) | IL2ABL1 | |
| SCHEMBL13730942 | 0.82 | IL2 (0.51) | IL2KDM4EMAPTABL1 | |
| SCHEMBL13838453 | 0.81 | IL2 (0.50) | IL2ABL1 | |
| SCHEMBL13838562 | 0.81 | IL2 (0.48) | IL2ABL1 | |
| SCHEMBL13729037 | 0.78 | IL2 (0.47) | IL2GAAABL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012151355-A1 | COMPOUNDS FOR INFLAMMATION AND IMMUNE-RELATED USES | SYNTA PHARMACEUTICALS CORP. (US) | 2012-11-08 | — | — | WO | disclosed |