Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IL2 | P60568 | 8/20 | 0.43 |
| ▸ | ABL1 | P00519 | 5/20 | 0.39 |
| ▸ | MAP4K1 | Q92918 | 4/20 | 0.35 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.35 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13838577 | 0.89 | IL2 (0.35) | IL2ABL1MAP4K1CSNK1DCSNK1E | |
| SCHEMBL13838419 | 0.79 | STIM1 (0.40) | IL2ABL1 | |
| SCHEMBL13727779 | 0.77 | IL2 (0.51) | IL2ABL1MAP4K1 | |
| SCHEMBL13729449 | 0.77 | IL2 (0.51) | IL2ABL1MAP4K1 | |
| SCHEMBL13838505 | 0.76 | IL2 (0.53) | IL2CSNK1DCSNK1E | |
| SCHEMBL13838584 | 0.76 | SCN9A (0.34) | IL2ABL1 | |
| SCHEMBL13838385 | 0.75 | IL2 (0.54) | IL2CSNK1DCSNK1E | |
| SCHEMBL13727394 | 0.75 | IL2 (0.46) | IL2ABL1MAP4K1 | |
| SCHEMBL13838418 | 0.75 | STIM1 (0.38) | IL2ABL1MAP4K1CSNK1DCSNK1E | |
| SCHEMBL13838562 | 0.75 | IL2 (0.48) | IL2ABL1CSNK1DCSNK1E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012151355-A1 | COMPOUNDS FOR INFLAMMATION AND IMMUNE-RELATED USES | SYNTA PHARMACEUTICALS CORP. (US) | 2012-11-08 | — | — | WO | disclosed |