Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 11/20 | 0.41 |
| ▸ | IL2 | P60568 | 2/20 | 0.39 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.38 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.38 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.37 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.37 |
| ▸ | KLRK1 | P26718 | 1/20 | 0.37 |
| ▸ | MICA | Q29983 | 1/20 | 0.37 |
| ▸ | RAET1L | Q5VY80 | 1/20 | 0.37 |
| ▸ | WNT3A | P56704 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13838325 | 0.93 | CSNK1D (0.37) | ABL1IL2ABCB1ABCC1CSNK1D | |
| SCHEMBL13838572 | 0.80 | IL2 (0.37) | ABL1IL2 | |
| SCHEMBL13838602 | 0.77 | ABL1 (0.43) | ABL1IL2ABCB1ABCC1CSNK1D | |
| SCHEMBL19228843 | 0.77 | ABL1 (0.42) | ABL1IL2ABCB1ABCC1 | |
| SCHEMBL13838516 | 0.76 | ABL1 (0.49) | ABL1IL2ABCB1ABCC1 | |
| SCHEMBL13838456 | 0.74 | NPC1 (0.47) | ABL1IL2ABCB1ABCC1 | |
| SCHEMBL15806437 | 0.74 | ABL1 (0.43) | ABL1IL2ABCB1ABCC1CSNK1D | |
| SCHEMBL13838578 | 0.72 | DYRK1A (0.52) | ABL1CSNK1DCSNK1E | |
| SCHEMBL13728434 | 0.72 | ABL1 (0.46) | ABL1ABCB1ABCC1 | |
| SCHEMBL13730219 | 0.72 | ABL1 (0.43) | ABL1IL2ABCB1ABCC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012151355-A1 | COMPOUNDS FOR INFLAMMATION AND IMMUNE-RELATED USES | SYNTA PHARMACEUTICALS CORP. (US) | 2012-11-08 | — | — | WO | disclosed |