Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK1D | P48730 | 1/20 | 0.37 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | ABL1 | P00519 | 2/20 | 0.36 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.36 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.36 |
| ▸ | WNT3A | P56704 | 2/20 | 0.36 |
| ▸ | KLRK1 | P26718 | 2/20 | 0.36 |
| ▸ | MICA | Q29983 | 2/20 | 0.36 |
| ▸ | RAET1L | Q5VY80 | 2/20 | 0.36 |
| ▸ | IL2 | P60568 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | XIAP | P98170 | 1/20 | 0.35 |
| ▸ | BIRC2 | Q13490 | 1/20 | 0.35 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.35 |
| ▸ | TEK | Q02763 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13838605 | 0.93 | ABL1 (0.41) | CSNK1DCSNK1EABL1ABCB1ABCC1 | |
| SCHEMBL19228842 | 0.78 | ABCB1 (0.39) | NPC1RAB9AHTTALOX15ABCB1 | |
| SCHEMBL13838572 | 0.77 | IL2 (0.37) | ABL1IL2 | |
| SCHEMBL15803780 | 0.77 | NPC1 (0.43) | NPC1RAB9AHTTALOX15ABCB1 | |
| SCHEMBL13838416 | 0.77 | PORCN (0.44) | NPC1RAB9AHTTALOX15ABCB1 | |
| SCHEMBL13838528 | 0.77 | RAB9A (0.42) | NPC1RAB9AHTTALOX15ABCB1 | |
| SCHEMBL13838334 | 0.76 | F10 (0.46) | CSNK1DCSNK1ENPC1RAB9AHTT | |
| SCHEMBL13838400 | 0.73 | DYRK1A (0.50) | CSNK1DCSNK1E | |
| SCHEMBL13838423 | 0.73 | ABCB1 (0.43) | NPC1RAB9AHTTALOX15ABCB1 | |
| SCHEMBL13728419 | 0.73 | GRM5 (0.42) | NPC1RAB9AHTTALOX15ABL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012151355-A1 | COMPOUNDS FOR INFLAMMATION AND IMMUNE-RELATED USES | SYNTA PHARMACEUTICALS CORP. (US) | 2012-11-08 | — | — | WO | disclosed |