Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNA3 | P22001 | 1/20 | 0.43 |
| ▸ | EGFR | P00533 | 1/20 | 0.40 |
| ▸ | PIM1 | P11309 | 1/20 | 0.40 |
| ▸ | ELANE | P08246 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | NSD2 | O96028 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.39 |
| ▸ | SRC | P12931 | 1/20 | 0.39 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.39 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.39 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13839613 | 0.85 | KCNA3 (0.51) | KCNA3EGFRPIM1ELANEMAPT | |
| SCHEMBL13839574 | 0.85 | ANPEP (0.41) | MAPTMAPK1KDM4EALDH1A1MEN1 | |
| SCHEMBL674709 | 0.82 | MAPK1 (0.47) | MAPK1KDM4EALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL13839600 | 0.81 | ELANE (0.49) | KCNA3EGFRPIM1ELANEMAPT | |
| SCHEMBL13839610 | 0.81 | EGFR (0.54) | EGFRPIM1ELANEMAPTKDM4E | |
| SCHEMBL13839607 | 0.79 | ALDH1A1 (0.52) | KCNA3EGFRPIM1ELANEMAPT | |
| SCHEMBL8989572 | 0.79 | MAPK1 (0.38) | MAPTMAPK1ALDH1A1LMNAHPGD | |
| SCHEMBL13841164 | 0.78 | ALDH1A1 (0.42) | KCNA3EGFRPIM1ELANEMAPT | |
| SCHEMBL13839602 | 0.77 | EGFR (0.40) | KCNA3EGFRPIM1ELANEMAPT | |
| SCHEMBL13839617 | 0.77 | ELANE (0.40) | KCNA3EGFRPIM1ELANEMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7531682-B2 | Method for making nitrile compounds from ethylenically unsaturated compounds | RHODIA POLYAMIDE INTERMEDIATES (FR) | 2009-05-12 | — | — | US | disclosed |
| US-7531682-B2 | Method for making nitrile compounds from ethylenically unsaturated compounds | RHODIA POLYAMIDE INTERMEDIATES (FR) | 2009-05-12 | — | — | US | disclosed |
| US-7253298-B2 | Hydrocyanating an unsaturated aliphatic nitrile, or a linear pentenenitrile in a liquid medium with hydrogen cyanide in the presence of a Nickel catalyst with an triaryl phosphite ligand; isomerization | RHODIA POLYAMIDE INTERMEDIATES (FR) | 2007-08-07 | — | — | US | disclosed |
| US-7253298-B2 | Hydrocyanating an unsaturated aliphatic nitrile, or a linear pentenenitrile in a liquid medium with hydrogen cyanide in the presence of a Nickel catalyst with an triaryl phosphite ligand; isomerization | RHODIA POLYAMIDE INTERMEDIATES (FR) | 2007-08-07 | — | — | US | disclosed |