Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | ELANE | P08246 | 3/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13839617 | 0.85 | ELANE (0.40) | NPC1LMNAL3MBTL1ELANE | |
| SCHEMBL13839579 | 0.85 | LMNA (0.39) | NPC1LMNAL3MBTL1POLBTSHR | |
| SCHEMBL3961009 | 0.80 | LMNA (0.48) | LMNAL3MBTL1TSHRNPSR1 | |
| SCHEMBL11680961 | 0.79 | LMNA (0.47) | LMNAL3MBTL1TSHRNPSR1 | |
| SCHEMBL14424022 | 0.77 | ELANE (0.35) | NPC1LMNAELANE | |
| SCHEMBL13839600 | 0.75 | ELANE (0.49) | NPC1LMNAL3MBTL1ELANETSHR | |
| SCHEMBL13839478 | 0.75 | LMNA (0.51) | NPC1LMNAL3MBTL1 | |
| SCHEMBL2603664 | 0.73 | MAPT (0.43) | NPC1LMNAL3MBTL1POLBTSHR | |
| SCHEMBL13839457 | 0.72 | LMNA (0.42) | NPC1LMNAL3MBTL1POLBTSHR | |
| SCHEMBL13839610 | 0.72 | EGFR (0.54) | NPC1LMNAELANEHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7531682-B2 | Method for making nitrile compounds from ethylenically unsaturated compounds | RHODIA POLYAMIDE INTERMEDIATES (FR) | 2009-05-12 | — | — | US | disclosed |
| US-7531682-B2 | Method for making nitrile compounds from ethylenically unsaturated compounds | RHODIA POLYAMIDE INTERMEDIATES (FR) | 2009-05-12 | — | — | US | disclosed |
| US-7253298-B2 | Hydrocyanating an unsaturated aliphatic nitrile, or a linear pentenenitrile in a liquid medium with hydrogen cyanide in the presence of a Nickel catalyst with an triaryl phosphite ligand; isomerization | RHODIA POLYAMIDE INTERMEDIATES (FR) | 2007-08-07 | — | — | US | disclosed |
| US-7253298-B2 | Hydrocyanating an unsaturated aliphatic nitrile, or a linear pentenenitrile in a liquid medium with hydrogen cyanide in the presence of a Nickel catalyst with an triaryl phosphite ligand; isomerization | RHODIA POLYAMIDE INTERMEDIATES (FR) | 2007-08-07 | — | — | US | disclosed |