SCHEMBL13839883

SCHEMBL13839883

C=CC(=O)Oc1ccc(N(C)c2ccc(OC(=O)C=C)cc2)cc1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
THRB P10828 4/20 0.54
RAB9A P51151 2/20 0.45
KMT2A Q03164 3/20 0.37
MEN1 O00255 2/20 0.37
ELANE P08246 2/20 0.37
NPSR1 Q6W5P4 1/20 0.37
BCL2A1 Q16548 2/20 0.36
TUBB4A P04350 1/20 0.36
TUBB P07437 1/20 0.36
TUBA3C P0DPH7 1/20 0.36
TUBA1B P68363 1/20 0.36
TUBA4A P68366 1/20 0.36
TUBB4B P68371 1/20 0.36
TUBB3 Q13509 1/20 0.36
TUBB2A Q13885 1/20 0.36
TUBB8 Q3ZCM7 1/20 0.36
TUBA3E Q6PEY2 1/20 0.36
TUBA1A Q71U36 1/20 0.36
TUBA1C Q9BQE3 1/20 0.36
TUBB6 Q9BUF5 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13777442 0.95 THRB (0.50) THRBRAB9AKMT2AMEN1ELANE
SCHEMBL13777505 0.95 THRB (0.50) THRBRAB9AKMT2AMEN1ELANE
SCHEMBL13777534 0.92 THRB (0.47) THRBRAB9AKMT2AMEN1NPSR1
SCHEMBL13777537 0.92 THRB (0.47) THRBRAB9AKMT2AMEN1NPSR1
SCHEMBL13777536 0.92 ELANE (0.49) THRBRAB9AELANEL3MBTL1ALDH1A1
SCHEMBL13777538 0.90 THRB (0.50) THRBRAB9AL3MBTL1KDM4EALDH1A1
SCHEMBL13777533 0.90 THRB (0.67) THRBRAB9AKMT2AMEN1ELANE
SCHEMBL13777539 0.90 THRB (0.67) THRBRAB9AKMT2AMEN1ELANE
SCHEMBL1263952 0.89 THRB (0.54) THRBRAB9AKMT2AMEN1TDP1
SCHEMBL13777514 0.87 THRB (0.44) THRBRAB9AKMT2AMEN1ELANE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1734410-B1 ELECTROPHOTOGRAPHY PHOTOSENSITIVE BODY, METHOD FOR PRODUCING ELECTROPHOTOGRAPHY PHOTOSENSITIVE BODY, PROCESS CARTRIDGE, AND ELECTROPHOTOGRAPH CANON KK (JP) 2016-05-11 EP disclosed
US-7534534-B2 Electrophotographic Photosensitive member, method for manufacturing electrophotographic photosensitive member, process cartridge and electrophotographic apparatus CANON KABUSHIKI KAISHA (JP) 2009-05-19 US disclosed
US-7534534-B2 Electrophotographic Photosensitive member, method for manufacturing electrophotographic photosensitive member, process cartridge and electrophotographic apparatus CANON KABUSHIKI KAISHA (JP) 2009-05-19 US disclosed
US-7378205-B2 Electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus CANON KABUSHIKI KAISHA (JP) 2008-05-27 US disclosed
US-7378205-B2 Electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus CANON KABUSHIKI KAISHA (JP) 2008-05-27 US disclosed
US-7272344-B2 Image forming method capable of maintaining sustained stable cleaning performance without causing an image smearing phenomenon even with a high strength and high abrasion image bearing member CANON KABUSHIKI KAISHA (JP) 2007-09-18 US disclosed
US-7272344-B2 Image forming method capable of maintaining sustained stable cleaning performance without causing an image smearing phenomenon even with a high strength and high abrasion image bearing member CANON KABUSHIKI KAISHA (JP) 2007-09-18 US disclosed
US-7226711-B2 Electrophotographic photosensitive member, method for manufacturing electrophotographic photosensitive member, process cartridge and electrophotographic apparatus CANON KABUSHIKI KAISHA (JP) 2007-06-05 US disclosed
US-7226711-B2 Electrophotographic photosensitive member, method for manufacturing electrophotographic photosensitive member, process cartridge and electrophotographic apparatus CANON KABUSHIKI KAISHA (JP) 2007-06-05 US disclosed
US-7186489-B2 Electrophotographic photosensitive member, electrophotographic photosensitive member manufacturing process, process cartridge, and electrophotographic apparatus CANON KABUSHIKI KAISHA (JP) 2007-03-06 US disclosed
US-7186489-B2 Electrophotographic photosensitive member, electrophotographic photosensitive member manufacturing process, process cartridge, and electrophotographic apparatus CANON KABUSHIKI KAISHA (JP) 2007-03-06 US disclosed