Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC4 | P56524 | 2/20 | 0.43 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.39 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.39 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.39 |
| ▸ | SLC18A3 | Q16572 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27372207 | 0.92 | OPRM1 (0.47) | OPRM1OPRD1OPRK1OPRL1 | |
| SCHEMBL4663612 | 0.91 | HDAC4 (0.44) | HDAC4OPRM1OPRL1SLC18A3 | |
| SCHEMBL19517969 | 0.90 | HDAC4 (0.41) | HDAC4OPRM1OPRL1SLC18A3 | |
| SCHEMBL4663547 | 0.90 | HDAC4 (0.41) | HDAC4OPRM1OPRL1SLC18A3 | |
| SCHEMBL4663735 | 0.90 | HDAC4 (0.41) | HDAC4OPRM1OPRL1SLC18A3 | |
| SCHEMBL4663726 | 0.88 | HDAC4 (0.40) | HDAC4OPRM1OPRL1SLC18A3 | |
| SCHEMBL4664190 | 0.88 | OPRM1 (0.48) | OPRM1OPRD1OPRK1OPRL1SLC18A3 | |
| SCHEMBL4664126 | 0.86 | OPRM1 (0.42) | HDAC4OPRM1OPRD1OPRK1OPRL1 | |
| SCHEMBL4664192 | 0.85 | HDAC4 (0.46) | HDAC4OPRM1OPRD1OPRK1OPRL1 | |
| SCHEMBL4665456 | 0.85 | OPRM1 (0.48) | OPRM1OPRD1OPRK1OPRL1SLC18A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4737583-B2 | — | — | 2011-08-03 | — | — | JP | claimed |
| JP-2004527491-A | — | — | 2004-09-09 | — | — | JP | claimed |
| EP-1390023-A2 | PHARMACEUTICAL SALTS | Grünenthal GmbH (DE) | 2004-02-25 | — | — | EP | claimed |
| WO-2002067651-A2 | PHARMACEUTICAL SALTS | Grünenthal GmbH (DE) | 2002-09-06 | — | — | WO | claimed |
| WO-2002067916-A2 | PHARMACEUTICAL SALTS | Grünenthal GmbH (DE) | 2002-09-06 | — | — | WO | claimed |
| EP-1390023-A2 | PHARMACEUTICAL SALTS | Grünenthal GmbH (DE) | 2004-02-25 | — | — | EP | disclosed |
| WO-2002067651-A2 | PHARMACEUTICAL SALTS | Grünenthal GmbH (DE) | 2002-09-06 | — | — | WO | disclosed |
| WO-2002067916-A2 | PHARMACEUTICAL SALTS | Grünenthal GmbH (DE) | 2002-09-06 | — | — | WO | disclosed |