Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 20/20 | 0.75 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.49 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3917030 | 1.00 | ADRB2 (0.75) | ADRB2CHRM3ADRB1 | |
| SCHEMBL13840802 | 0.93 | ADRB2 (0.66) | ADRB2CHRM3ADRB1 | |
| SCHEMBL3917076 | 0.93 | ADRB2 (0.66) | ADRB2CHRM3ADRB1 | |
| SCHEMBL13840817 | 0.92 | ADRB2 (0.65) | ADRB2CHRM3ADRB1 | |
| SCHEMBL13840714 | 0.92 | ADRB2 (0.65) | ADRB2CHRM3ADRB1 | |
| SCHEMBL3924974 | 0.92 | ADRB2 (0.65) | ADRB2CHRM3ADRB1 | |
| SCHEMBL3914436 | 0.92 | ADRB2 (0.65) | ADRB2CHRM3ADRB1 | |
| SCHEMBL3921775 | 0.92 | ADRB2 (0.65) | ADRB2CHRM3ADRB1 | |
| SCHEMBL6506204 | 0.92 | ADRB2 (0.78) | ADRB2CHRM3ADRB1 | |
| SCHEMBL13840800 | 0.91 | ADRB2 (0.63) | ADRB2CHRM3ADRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1730141-B1 | COMPOUNDS FOR THE TREATMENT OF DISEASES | PFIZER LTD (GB) | 2009-05-27 | — | — | EP | disclosed |
| US-7538141-B2 | Compounds for the treatment of diseases | PFIZER INC. | 2009-05-26 | — | — | US | disclosed |
| US-7538141-B2 | Compounds for the treatment of diseases | PFIZER INC. | 2009-05-26 | — | — | US | disclosed |