Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 16/20 | 0.55 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3915467 | 1.00 | ADRB2 (0.55) | ADRB2CHRM3CA1CA2HSD17B2 | |
| SCHEMBL13840734 | 0.92 | ADRB2 (0.62) | ADRB2CHRM3 | |
| SCHEMBL3915421 | 0.92 | ADRB2 (0.62) | ADRB2CHRM3 | |
| SCHEMBL13840714 | 0.92 | ADRB2 (0.65) | ADRB2CHRM3MEN1ALDH1A1KMT2A | |
| SCHEMBL3914436 | 0.92 | ADRB2 (0.65) | ADRB2CHRM3MEN1ALDH1A1KMT2A | |
| SCHEMBL13840735 | 0.90 | ADRB2 (0.58) | ADRB2CHRM3CA1CA2HSD17B2 | |
| SCHEMBL3918557 | 0.90 | ADRB2 (0.58) | ADRB2CHRM3CA1CA2HSD17B2 | |
| SCHEMBL3925018 | 0.87 | ADRB2 (0.60) | ADRB2CHRM3MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL13840696 | 0.87 | NPC1 (0.47) | ADRB2ALDH1A1SMN1; SMN2 | |
| SCHEMBL3917066 | 0.87 | NPC1 (0.47) | ADRB2ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7538141-B2 | Compounds for the treatment of diseases | PFIZER INC. | 2009-05-26 | — | — | US | disclosed |
| US-7538141-B2 | Compounds for the treatment of diseases | PFIZER INC. | 2009-05-26 | — | — | US | disclosed |