Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL2 | P10415 | 1/20 | 0.42 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.38 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.38 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13652843 | 0.87 | BCL2 (0.39) | BCL2BCL2L1ALOX5PTPN1PTPN2 | |
| SCHEMBL12733195 | 0.85 | HSPA5 (0.44) | ALOX5ALDH1A1SMN1; SMN2CYP2D6CYP2C19 | |
| SCHEMBL10871265 | 0.82 | BCL2 (0.52) | BCL2BCL2L1ALOX5PTPN1PTPN2 | |
| SCHEMBL12733199 | 0.82 | HSPA5 (0.41) | SMN1; SMN2CYP2D6CYP2C19 | |
| SCHEMBL13840732 | 0.82 | BCL2 (0.46) | BCL2BCL2L1ALOX5PTPN1PTPN2 | |
| SCHEMBL13840739 | 0.81 | PTPN1 (0.53) | BCL2BCL2L1ALOX5PTPN1PTPN2 | |
| SCHEMBL12733192 | 0.81 | HSPA5 (0.57) | ALDH1A1SMN1; SMN2CYP2D6CYP2C19 | |
| SCHEMBL11212329 | 0.81 | BCL2 (0.50) | BCL2BCL2L1ALOX5PTPN1PTPN2 | |
| SCHEMBL12733198 | 0.79 | CYP2C19 (0.35) | ALDH1A1SMN1; SMN2CYP2D6CYP2C19 | |
| SCHEMBL14323973 | 0.79 | NPC1 (0.43) | BCL2BCL2L1PTPN1PTPN2PTPN6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7534539-B2 | Electrophotographic photoreceptor and image forming apparatus having the same | SHARP KABUSHIKI KAISHA (JP) | 2009-05-19 | — | — | US | disclosed |