Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIT | P10721 | 1/20 | 0.36 |
| ▸ | EGFR | P00533 | 17/20 | 0.34 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.33 |
| ▸ | ABL1 | P00519 | 2/20 | 0.31 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.31 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.31 |
| ▸ | SRC | P12931 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2835023 | 0.70 | KIT (0.46) | KITEGFRENPP1SRC | |
| SCHEMBL13844485 | 0.67 | CLK1 (0.54) | EGFRABL1PDGFRBFGFR1SRC | |
| SCHEMBL2840274 | 0.66 | ENPP1 (0.49) | KITEGFRENPP1SRC | |
| SCHEMBL24393381 | 0.62 | EGFR (0.46) | EGFRABL1PDGFRBFGFR1SRC | |
| SCHEMBL1012990 | 0.59 | EGFR (0.52) | EGFRABL1PDGFRBFGFR1SRC | |
| SCHEMBL16253984 | 0.58 | EGFR (0.49) | EGFRABL1PDGFRBFGFR1SRC | |
| SCHEMBL24391745 | 0.58 | EGFR (0.43) | EGFRABL1PDGFRBFGFR1SRC | |
| SCHEMBL20865361 | 0.57 | EGFR (0.48) | EGFRABL1PDGFRBFGFR1SRC | |
| SCHEMBL20865317 | 0.57 | CLK4 (0.44) | EGFRABL1PDGFRBFGFR1SRC | |
| SCHEMBL3520125 | 0.57 | CLK4 (0.62) | EGFRABL1PDGFRBFGFR1SRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009057139-A2 | NOVEL 4-(TETRAZOL-5-YL)-QUINAZOLINE DERIVATIVES AS ANTI CANCER AGENTS | NATCO PHARMA LIMITED (IN) | 2009-05-07 | — | — | WO | disclosed |