Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 17/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 5/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13844665 | 0.84 | EPHX2 (0.45) | LTA4HKCNH2EPHX2 | |
| SCHEMBL13844690 | 0.83 | LTA4H (0.43) | LTA4HKCNH2EPHX2 | |
| SCHEMBL13844799 | 0.80 | LTA4H (0.45) | LTA4HKCNH2EPHX2 | |
| SCHEMBL13844734 | 0.79 | LTA4H (0.52) | LTA4HKCNH2EPHX2 | |
| SCHEMBL13844686 | 0.78 | LTA4H (0.49) | LTA4HKCNH2EPHX2 | |
| SCHEMBL13844732 | 0.77 | LTA4H (0.46) | LTA4HKCNH2EPHX2 | |
| SCHEMBL13844619 | 0.76 | LTA4H (0.45) | LTA4HKCNH2EPHX2 | |
| SCHEMBL1906945 | 0.76 | LTA4H (0.71) | LTA4HKCNH2 | |
| SCHEMBL1906946 | 0.76 | LTA4H (0.71) | LTA4HKCNH2 | |
| SCHEMBL13844695 | 0.75 | LTA4H (0.44) | LTA4HKCNH2EPHX2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009058347-A1 | ARYL-SUBSTITUTED BRIDGED OR FUSED DIAMINES AS MODULATORS OF LEUKOTRIENE A4 HYDROLASE | JANSSEN PHARMACEUTICA N.V. (BE) | 2009-05-07 | — | — | WO | disclosed |