⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14199070 | 0.77 | — | — | |
| SCHEMBL14996695 | 0.77 | — | — | |
| SCHEMBL19661047 | 0.72 | — | — | |
| SCHEMBL19977977 | 0.71 | — | — | |
| SCHEMBL13926008 | 0.62 | — | — | |
| SCHEMBL14339632 | 0.61 | — | — | |
| SCHEMBL13679279 | 0.61 | — | — | |
| SCHEMBL14114396 | 0.60 | — | — | |
| SCHEMBL20993122 | 0.59 | — | — | |
| SCHEMBL23129841 | 0.59 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009059162-A1 | CYTOKINE INHIBITORS | HUTCHISON MEDIPHARMA ENTERPRISES LIMITED (BS) | 2009-05-07 | — | — | WO | disclosed |
| WO-2008079880-A1 | 6-AMINOIMIDAZO[1,2-B]PYRIDAZINE ANALOGS AS RHO KINASE INHIBITORS FOR THE TREATMENT OF GLAUCOMA AND OCULAR HYPERTENSION | ALCON RESEARCH, LTD. (US) | 2008-07-03 | — | — | WO | disclosed |