Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 10/20 | 0.57 |
| ▸ | CD40 | P25942 | 1/20 | 0.49 |
| ▸ | CD40LG | P29965 | 1/20 | 0.49 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.46 |
| ▸ | PRMT1 | Q99873 | 2/20 | 0.42 |
| ▸ | PRMT3 | O60678 | 1/20 | 0.42 |
| ▸ | EP300 | Q09472 | 1/20 | 0.42 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.42 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | PHLPP2 | Q6ZVD8 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13845525 | 0.93 | ENPP2 (0.68) | ENPP2CD40CD40LGPTPN11PRMT1 | |
| SCHEMBL14001725 | 0.82 | CD40 (0.55) | ENPP2CD40CD40LGPTPN11CYP1A2 | |
| SCHEMBL12975927 | 0.82 | CD40 (0.56) | ENPP2CD40CD40LGPRMT1PRMT3 | |
| SCHEMBL13615187 | 0.81 | ENPP2 (0.43) | ENPP2CD40CD40LGPTPN11CYP1A2 | |
| SCHEMBL12975956 | 0.80 | ENPP2 (0.44) | ENPP2CD40CD40LGPTPN11PRMT1 | |
| SCHEMBL13088674 | 0.80 | ENPP2 (0.45) | ENPP2CD40CD40LGPTPN11PRMT1 | |
| SCHEMBL13615140 | 0.79 | PTPN11 (0.45) | ENPP2CD40CD40LGPTPN11CYP1A2 | |
| SCHEMBL13845513 | 0.79 | ENPP2 (0.43) | ENPP2CD40CD40LGPTPN11PRMT1 | |
| SCHEMBL13860901 | 0.78 | ENPP2 (0.40) | ENPP2CD40CD40LGPTPN11PRMT1 | |
| SCHEMBL13088681 | 0.78 | ENPP2 (0.46) | ENPP2CD40CD40LGPTPN11PRMT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7531009-B2 | 6-azo-5,5′-dihydroxy-7,7′-disulfo-2-2′ dinaphthylamine derivatives | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 2009-05-12 | — | — | US | disclosed |
| US-20080196180-A1 | 6-Azo-5,5'-Dihydroxy-7,7'-Disulfo-2-2' Dinaphthylamine Derivatives | CIBA SPECIALTY CHEMICALS CORP. | 2008-08-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080196180-A1 | 6-Azo-5,5'-Dihydroxy-7,7'-Disulfo-2-2' Dinaphthylamine Derivatives | H1-5, DHODH, DDT | ENPP2 1644/4885CD40 4510/4885CD40LG 3210/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.