Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGES | O14684 | 2/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | SCN9A | Q15858 | 3/20 | 0.38 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.38 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.38 |
| ▸ | F10 | P00742 | 1/20 | 0.37 |
| ▸ | CYSLTR1 | Q9Y271 | 2/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.37 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL979257 | 0.84 | PTGES (0.74) | PTGESNPC1HPGDRAB9ASMN1; SMN2 | |
| SCHEMBL13850969 | 0.84 | PTGES (0.47) | PTGESNPC1HPGDRAB9ASMN1; SMN2 | |
| SCHEMBL979376 | 0.83 | PTGES (0.75) | PTGESNPC1HPGDRAB9ASMN1; SMN2 | |
| SCHEMBL13850721 | 0.83 | PTGES (0.48) | PTGESNPC1HPGDRAB9ASMN1; SMN2 | |
| SCHEMBL979290 | 0.81 | PTGES (0.53) | PTGESKAT6A | |
| SCHEMBL979144 | 0.81 | PTGES (0.81) | PTGESKAT6ACYSLTR1CYSLTR2 | |
| SCHEMBL13850892 | 0.80 | PTGES (0.50) | PTGESNPC1SCN9ASCN5AKAT6A | |
| SCHEMBL13066220 | 0.79 | PTGES (0.50) | PTGESSCN9AKAT6ACYSLTR1EPHX2 | |
| SCHEMBL13850885 | 0.79 | PTGES (0.51) | PTGESNPC1SCN9ASCN5AF10 | |
| SCHEMBL13850720 | 0.79 | PTGES (0.49) | PTGESSCN9AKAT6A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009064250-A1 | BIS-(SULFONYLAMINO) DERIVATIVES IN THERAPY 065 | ASTRAZENECA AB (SE) | 2009-05-22 | — | — | WO | disclosed |
| WO-2009064251-A1 | BIS-(SULFONYLAMINO) DERIVATIVES IN THERAPY 066 | ASTRAZENECA AB (SE) | 2009-05-22 | — | — | WO | disclosed |