Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 17/20 | 0.48 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.38 |
| ▸ | F2 | P00734 | 2/20 | 0.38 |
| ▸ | TACR1 | P25103 | 1/20 | 0.38 |
| ▸ | HPN | P05981 | 1/20 | 0.37 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.37 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.37 |
| ▸ | ST14 | Q9Y5Y6 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1385388 | 0.92 | F10 (0.49) | F10PRSS1HPNPRSS2PRSS3 | |
| SCHEMBL1385978 | 0.90 | F10 (0.39) | F10PRSS1F2TACR1 | |
| SCHEMBL4392721 | 0.84 | F10 (0.57) | F10 | |
| SCHEMBL1385980 | 0.83 | F2 (0.39) | F10PRSS1F2HPNST14 | |
| SCHEMBL1385984 | 0.83 | F2 (0.39) | F10PRSS1F2HPNST14 | |
| SCHEMBL4392716 | 0.81 | F10 (0.54) | F10 | |
| SCHEMBL4397193 | 0.81 | F10 (0.56) | F10 | |
| SCHEMBL27572570 | 0.80 | F10 (0.52) | F10F2 | |
| SCHEMBL1386137 | 0.79 | F10 (0.51) | F10PRSS1F2HPNPRSS2 | |
| SCHEMBL1386872 | 0.79 | F10 (0.40) | F10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4829449-B2 | — | — | 2011-12-07 | — | — | JP | claimed |
| JP-2003508353-A | — | — | 2003-03-04 | — | — | JP | claimed |
| EP-1208097-A2 | SUBSTITUTED OXOAZAHETEROCYCLYL COMPOUNDS | Aventis Pharmaceuticals Inc. (US) | 2002-05-29 | — | — | EP | claimed |
| WO-2001007436-A2 | SUBSTITUTED OXOAZAHETEROCYCLYL COMPOUNDS | AVENTIS PHARMACEUTICALS INC. (US) | 2001-02-01 | — | — | WO | claimed |