Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 15/20 | 0.40 |
| ▸ | PARP1 | P09874 | 2/20 | 0.33 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.33 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.33 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.33 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.33 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1385978 | 0.90 | F10 (0.39) | F10 | |
| SCHEMBL4397531 | 0.88 | F10 (0.37) | F10MAP4K4 | |
| SCHEMBL1386137 | 0.86 | F10 (0.51) | F10 | |
| SCHEMBL4387285 | 0.84 | F10 (0.44) | F10MAP4K4 | |
| SCHEMBL1384686 | 0.79 | F10 (0.48) | F10 | |
| SCHEMBL1386877 | 0.79 | KCNH2 (0.35) | F10PIK3CDPIK3CAPIK3CBPIK3CG | |
| SCHEMBL1384276 | 0.79 | F10 (0.39) | F10MAP4K4 | |
| SCHEMBL1385388 | 0.78 | F10 (0.49) | F10 | |
| SCHEMBL7146942 | 0.77 | F10 (0.49) | F10MAP4K4 | |
| SCHEMBL4398522 | 0.76 | F10 (0.37) | F10MAP4K4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4829449-B2 | — | — | 2011-12-07 | — | — | JP | claimed |
| JP-2003508353-A | — | — | 2003-03-04 | — | — | JP | claimed |
| EP-1208097-A2 | SUBSTITUTED OXOAZAHETEROCYCLYL COMPOUNDS | Aventis Pharmaceuticals Inc. (US) | 2002-05-29 | — | — | EP | claimed |
| WO-2001007436-A2 | SUBSTITUTED OXOAZAHETEROCYCLYL COMPOUNDS | AVENTIS PHARMACEUTICALS INC. (US) | 2001-02-01 | — | — | WO | claimed |