Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 1/20 | 0.42 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.42 |
| ▸ | ITGAV | P06756 | 1/20 | 0.42 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.42 |
| ▸ | ITGB5 | P18084 | 1/20 | 0.42 |
| ▸ | ITGB6 | P18564 | 1/20 | 0.42 |
| ▸ | ITGB8 | P26012 | 1/20 | 0.42 |
| ▸ | RPS6KB1 | P23443 | 19/20 | 0.38 |
| ▸ | AKT1 | P31749 | 19/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12348224 | 0.93 | ITGAV (0.41) | ITGB3ITGB1ITGAVITGA5ITGB5 | |
| SCHEMBL8354533 | 0.90 | ITGB3 (0.41) | ITGB3ITGB1ITGAVITGA5ITGB5 | |
| SCHEMBL2231372 | 0.89 | ITGB3 (0.40) | ITGB3ITGB1ITGAVITGA5ITGB5 | |
| SCHEMBL2231362 | 0.89 | ITGB3 (0.40) | ITGB3ITGB1ITGAVITGA5ITGB5 | |
| SCHEMBL2233704 | 0.84 | ITGAV (0.39) | ITGB3ITGB1ITGAVITGA5ITGB5 | |
| SCHEMBL12348309 | 0.82 | ITGB3 (0.44) | ITGB3ITGB1ITGAVITGA5ITGB5 | |
| SCHEMBL2411809 | 0.82 | ITGAV (0.51) | ITGB3ITGB1ITGAVITGA5ITGB5 | |
| SCHEMBL2234185 | 0.81 | ITGAV (0.40) | ITGB3ITGB1ITGAVITGA5ITGB5 | |
| SCHEMBL2232298 | 0.80 | ITGB3 (0.43) | ITGB3ITGB1ITGAVITGA5ITGB5 | |
| SCHEMBL13848509 | 0.80 | RPS6KB1 (0.44) | ITGB3ITGB1ITGAVITGA5ITGB5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1565467-B1 | NOVEL VITRONECTIN RECEPTOR ANTAGONIST DERIVATIVES, METHOD FOR PREPARING SAME, USE THEREOF AS MEDICINES AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | GALAPAGOS SAS (FR) | 2009-05-20 | — | — | EP | disclosed |