Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14298443 | 0.93 | BRAF (0.49) | BRAFMAPK14 | |
| SCHEMBL13848985 | 0.91 | BRAF (0.47) | BRAF | |
| SCHEMBL13848971 | 0.90 | BRAF (0.46) | BRAFMAPK14 | |
| SCHEMBL13848846 | 0.90 | BRAF (0.48) | BRAF | |
| SCHEMBL13848650 | 0.86 | BRAF (0.53) | BRAF | |
| SCHEMBL13848669 | 0.86 | BRAF (0.52) | BRAF | |
| SCHEMBL13848646 | 0.85 | BRAF (0.49) | BRAF | |
| SCHEMBL13887493 | 0.85 | BRAF (0.48) | BRAFMAPK14 | |
| SCHEMBL13848820 | 0.85 | BRAF (0.49) | BRAFMAPK14 | |
| SCHEMBL13887556 | 0.85 | BRAF (0.48) | BRAF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1725544-B1 | 3-[4-HETEROCYCLYL-1,2,3-TRIAZOL-1-YL]-N-ARYL-BENZAMIDES AS INHIBITORS OF THE CYTOKINES PRODUCTION FOR THE TREATMENT OF CHRONIC INFLAMMATORY DISEASES | BOEHRINGER INGELHEIM PHARMA (US) | 2009-05-27 | — | — | EP | disclosed |