Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRAF | P15056 | 19/20 | 0.48 |
| ▸ | LYN | P07948 | 1/20 | 0.46 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14298443 | 0.90 | BRAF (0.49) | BRAF | |
| SCHEMBL13848675 | 0.90 | BRAF (0.49) | BRAF | |
| SCHEMBL13848985 | 0.88 | BRAF (0.47) | BRAF | |
| SCHEMBL13848971 | 0.86 | BRAF (0.46) | BRAF | |
| SCHEMBL13848744 | 0.86 | BRAF (0.49) | BRAFLYNMAPK9 | |
| SCHEMBL13887591 | 0.85 | BRAF (0.48) | BRAFLYNMAPK9 | |
| SCHEMBL13887496 | 0.84 | BRAF (0.47) | BRAFLYNMAPK9 | |
| SCHEMBL13887576 | 0.84 | BRAF (0.49) | BRAFLYNMAPK9 | |
| SCHEMBL13848835 | 0.83 | BRAF (0.48) | BRAFLYNMAPK9 | |
| SCHEMBL13848725 | 0.83 | BRAF (0.48) | BRAF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1725544-B1 | 3-[4-HETEROCYCLYL-1,2,3-TRIAZOL-1-YL]-N-ARYL-BENZAMIDES AS INHIBITORS OF THE CYTOKINES PRODUCTION FOR THE TREATMENT OF CHRONIC INFLAMMATORY DISEASES | BOEHRINGER INGELHEIM PHARMA (US) | 2009-05-27 | — | — | EP | disclosed |
| EP-1887003-A1 | 3-[4-HETEROCYCLYL -1,2,3-TRIAZOL-1-YL]-N-ARYL-BENZAMIDES AS INHIBITORS OF THE CYTOKINES PRODUCTION FOR THE TREATMENT OF CHRONIC INFLAMMATORY DISEASES | Boehringer Ingelheim Pharmaceuticals, Inc. (US) | 2008-02-13 | — | — | EP | disclosed |