Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRAF | P15056 | 20/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13848830 | 0.90 | BRAF (0.45) | BRAF | |
| SCHEMBL13887611 | 0.87 | BRAF (0.45) | BRAF | |
| SCHEMBL13848722 | 0.82 | BRAF (0.47) | BRAF | |
| SCHEMBL13887682 | 0.80 | BRAF (0.36) | BRAF | |
| SCHEMBL13848723 | 0.80 | BRAF (0.45) | BRAF | |
| SCHEMBL13848778 | 0.80 | BRAF (0.38) | BRAF | |
| SCHEMBL13848809 | 0.79 | BRAF (0.36) | BRAF | |
| SCHEMBL13848970 | 0.79 | BRAF (0.44) | BRAF | |
| SCHEMBL13848756 | 0.79 | BRAF (0.47) | BRAF | |
| SCHEMBL13848788 | 0.79 | BRAF (0.52) | BRAF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1725544-B1 | 3-[4-HETEROCYCLYL-1,2,3-TRIAZOL-1-YL]-N-ARYL-BENZAMIDES AS INHIBITORS OF THE CYTOKINES PRODUCTION FOR THE TREATMENT OF CHRONIC INFLAMMATORY DISEASES | BOEHRINGER INGELHEIM PHARMA (US) | 2009-05-27 | — | — | EP | disclosed |