Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.68 |
| ▸ | HPGD | P15428 | 4/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.62 |
| ▸ | MEN1 | O00255 | 1/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.62 |
| ▸ | MAPT | P10636 | 1/20 | 0.62 |
| ▸ | PKM | P14618 | 1/20 | 0.62 |
| ▸ | HTT | P42858 | 1/20 | 0.62 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.62 |
| ▸ | CA12 | O43570 | 2/20 | 0.53 |
| ▸ | CA1 | P00915 | 2/20 | 0.53 |
| ▸ | CA2 | P00918 | 2/20 | 0.53 |
| ▸ | CA9 | Q16790 | 2/20 | 0.53 |
| ▸ | CA3 | P07451 | 1/20 | 0.53 |
| ▸ | CA4 | P22748 | 1/20 | 0.53 |
| ▸ | CA6 | P23280 | 1/20 | 0.53 |
| ▸ | CA5A | P35218 | 1/20 | 0.53 |
| ▸ | CA7 | P43166 | 1/20 | 0.53 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4066967 | 0.83 | EGLN1 (0.66) | HSP90AA1KDM4EKMT2AMEN1ALDH1A1 | |
| SCHEMBL20677832 | 0.81 | HSP90AA1 (1.00) | HSP90AA1HPGDKMT2ACA12CA1 | |
| SCHEMBL13656899 | 0.79 | MEN1 (0.66) | HPGDKDM4EKMT2AMEN1ALDH1A1 | |
| SCHEMBL5860823 | 0.78 | NPC1 (0.71) | HSP90AA1HPGDKMT2AALDH1A1LMNA | |
| SCHEMBL485443 | 0.77 | HSD17B10 (1.00) | HPGDKDM4EKMT2AMEN1ALDH1A1 | |
| SCHEMBL9400432 | 0.77 | EGLN1 (0.66) | HPGDKDM4EKMT2AMEN1MAPT | |
| SCHEMBL11316839 | 0.77 | NAAA (0.59) | HPGDKDM4EKMT2AMEN1ALDH1A1 | |
| SCHEMBL11598238 | 0.77 | NAAA (0.59) | HPGDKDM4EKMT2AMEN1ALDH1A1 | |
| SCHEMBL9095008 | 0.77 | HPGD (0.51) | HSP90AA1HPGDKDM4EKMT2AMEN1 | |
| SCHEMBL9095674 | 0.76 | KDM4E (0.52) | HSP90AA1HPGDKDM4EKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1326865-B1 | AZA- AND POLYAZA-NAPHTHALENYL CARBOXAMIDES USEFUL AS HIV INTEGRASE INHIBITORS | MERCK & CO INC (US) | 2009-05-06 | — | — | EP | disclosed |