Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.58 |
| ▸ | THRB | P10828 | 1/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | CD69 | Q07108 | 1/20 | 0.50 |
| ▸ | LGALS8 | O00214 | 1/20 | 0.50 |
| ▸ | LGALS3 | P17931 | 1/20 | 0.50 |
| ▸ | LGALS4 | P56470 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12792638 | 1.00 | MAPK1 (0.62) | MAPK1ALDH1A1THRBMEN1KMT2A | |
| SCHEMBL25868457 | 1.00 | MAPK1 (0.62) | MAPK1ALDH1A1THRBMEN1KMT2A | |
| SCHEMBL13849178 | 0.92 | LGALS3 (0.59) | MAPK1ALDH1A1THRBMEN1KMT2A | |
| SCHEMBL12792627 | 0.89 | LGALS3 (0.67) | MAPK1ALDH1A1THRBMEN1KMT2A | |
| SCHEMBL24299984 | 0.88 | MAPK1 (0.61) | MAPK1ALDH1A1THRBMEN1KMT2A | |
| SCHEMBL24917470 | 0.87 | MAPK1 (0.67) | MAPK1ALDH1A1THRBMEN1KMT2A | |
| SCHEMBL26989024 | 0.86 | MAPK1 (0.47) | MAPK1ALDH1A1THRBMEN1KMT2A | |
| SCHEMBL14530114 | 0.86 | LGALS3 (0.63) | MAPK1ALDH1A1THRBCD69LGALS8 | |
| SCHEMBL13702248 | 0.86 | LGALS3 (0.63) | MAPK1ALDH1A1THRBCD69LGALS8 | |
| SCHEMBL25344300 | 0.85 | MAPK1 (0.71) | MAPK1ALDH1A1THRBMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2060584-A1 | Method for the production of proteins with chemically functionalized N-termini | Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) | 2009-05-20 | — | — | EP | disclosed |