Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLRA1 | P23415 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | CETP | P11597 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ELANE | P08246 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17549514 | 0.89 | GLRA1 (0.39) | GLRA1TSHRCETPALDH1A1KDM4E | |
| SCHEMBL3821872 | 0.88 | TSHR (0.41) | GLRA1TSHRELANE | |
| SCHEMBL19661152 | 0.81 | GLRA1 (0.43) | GLRA1ALDH1A1ELANE | |
| SCHEMBL28078446 | 0.80 | GLRA1 (0.60) | GLRA1TSHRALDH1A1 | |
| SCHEMBL12999214 | 0.79 | TSHR (0.39) | GLRA1TSHRELANE | |
| SCHEMBL5379773 | 0.78 | TSHR (0.61) | TSHRCETPALDH1A1ELANE | |
| Fospropofol SCHEMBL28702264 | 0.77 | TSHR (0.38) | TSHRELANE | |
| SCHEMBL17357038 | 0.77 | TSHR (0.49) | TSHRCETPALDH1A1KDM4EELANE | |
| Fospropofol SCHEMBL3821874 | 0.77 | GABRA1 (0.39) | GLRA1TSHR | |
| SCHEMBL14467274 | 0.77 | CYP3A4 (0.49) | TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7534776-B2 | Process for preparing water-soluble phosphonooxymethyl derivatives of alcohol and phenol | EISAI CORPORATION OF NORTH AMERICA (US) | 2009-05-19 | — | — | US | disclosed |
| US-7534776-B2 | Process for preparing water-soluble phosphonooxymethyl derivatives of alcohol and phenol | EISAI CORPORATION OF NORTH AMERICA (US) | 2009-05-19 | — | — | US | disclosed |
| EP-2058320-A1 | Process for preparing water-soluble phosphonooxymethyl derivatives of alcohol and phenol | GUILFORD PHARMACEUTICALS INC. (US) | 2009-05-13 | — | — | EP | disclosed |
| US-7244718-B2 | Water soluble prodrugs of hindered alcohols | UNIVERSITY OF KANSAS (US) | 2007-07-17 | — | — | US | disclosed |
| US-7229978-B2 | Process for preparing water soluble phosphonooxymethyl derivatives of alcohol and phenol | MGI GP, INC. (US) | 2007-06-12 | — | — | US | disclosed |
| US-7229978-B2 | Process for preparing water soluble phosphonooxymethyl derivatives of alcohol and phenol | MGI GP, INC. (US) | 2007-06-12 | — | — | US | disclosed |
| US-20070043206-A1 | Process for preparing water-soluble phosphonooxymethyl derivatives of alcohol and phenol | MGI GP, INC. (US) | 2007-02-22 | — | — | US | disclosed |
| US-20070043206-A1 | Process for preparing water-soluble phosphonooxymethyl derivatives of alcohol and phenol | MGI GP, INC. (US) | 2007-02-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070043206-A1 | Process for preparing water-soluble phosphonooxymethyl derivatives of alcohol and phenol | PHOSPHO1, CD69, CYP2E1 | GLRA1 2993/4885TSHR 3449/4885CETP 1806/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.