Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TUBB1 | Q9H4B7 | 2/20 | 0.61 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | CASP3 | P42574 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.31 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.31 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.31 |
| ▸ | STAT6 | P42226 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hemiasterlin SCHEMBL22692376 | 1.00 | TUBB1 (0.61) | TUBB1GLAALDH1A1SMN1; SMN2NR4A2 | |
| Hemiasterlin SCHEMBL14567797 | 1.00 | TUBB1 (0.61) | TUBB1GLAALDH1A1SMN1; SMN2NR4A2 | |
| Hemiasterlin SCHEMBL57334 | 1.00 | TUBB1 (0.61) | TUBB1GLAALDH1A1SMN1; SMN2NR4A2 | |
| Hemiasterlin SCHEMBL4173 | 1.00 | TUBB1 (0.61) | TUBB1GLAALDH1A1SMN1; SMN2NR4A2 | |
| Hemiasterlin SCHEMBL57313 | 1.00 | TUBB1 (0.61) | TUBB1GLAALDH1A1SMN1; SMN2NR4A2 | |
| Hemiasterlin SCHEMBL29421592 | 1.00 | TUBB1 (0.61) | TUBB1GLAALDH1A1SMN1; SMN2NR4A2 | |
| Hemiasterlin SCHEMBL14115433 | 1.00 | TUBB1 (0.61) | TUBB1GLAALDH1A1SMN1; SMN2NR4A2 | |
| Hemiasterlin SCHEMBL13203800 | 1.00 | TUBB1 (0.61) | TUBB1GLAALDH1A1SMN1; SMN2NR4A2 | |
| SCHEMBL26607783 | 0.94 | TUBB1 (0.53) | TUBB1GLAALDH1A1SMN1; SMN2NR4A2 | |
| SCHEMBL58604 | 0.93 | TUBB1 (0.52) | TUBB1GLAALDH1A1SMN1; SMN2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11744876-B2 | Immunomodulator antibody drug conjugates and uses thereof | SUTRO BIOPHARMA, INC. (US) | 2023-09-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11744876-B2 | Immunomodulator antibody drug conjugates and uses thereof | FCGR1A, FCGR2A, FCGRT | TUBB1 506/4885GLA 1571/4885ALDH1A1 702/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.