FCGR1A

High affinity immunoglobulin gamma Fc receptor I · P12314 · FCGR1A on Sugi Atlas →

641 patent compounds predicted against FCGR1A, 440 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

CompoundConfidenceSupporting neighbours
SCHEMBL13917176 SCHEMBL13917176 1.00 1/20
SCHEMBL13421296 SCHEMBL13421296 0.96 1/20
SCHEMBL13917185 SCHEMBL13917185 0.89 1/20
SCHEMBL13921798 SCHEMBL13921798 0.84 1/20
SCHEMBL13420987 SCHEMBL13420987 0.82 1/20
SCHEMBL13420936 SCHEMBL13420936 0.82 1/20
SCHEMBL13421092 SCHEMBL13421092 0.81 1/20
SCHEMBL13917179 SCHEMBL13917179 0.81 1/20
SCHEMBL13421360 SCHEMBL13421360 0.81 1/20
SCHEMBL13421062 SCHEMBL13421062 0.80 1/20
SCHEMBL13917183 SCHEMBL13917183 0.80 1/20
SCHEMBL13917186 SCHEMBL13917186 0.80 1/20
SCHEMBL13917188 SCHEMBL13917188 0.80 1/20
SCHEMBL3200004 SCHEMBL3200004 0.80 1/20
SCHEMBL13921832 SCHEMBL13921832 0.80 1/20
SCHEMBL13420995 SCHEMBL13420995 0.79 1/20
SCHEMBL13921837 SCHEMBL13921837 0.78 1/20
SCHEMBL13421038 SCHEMBL13421038 0.78 1/20
SCHEMBL13921814 SCHEMBL13921814 0.77 1/20
SCHEMBL13421029 SCHEMBL13421029 0.77 1/20

Clinical trials — most relevant to FCGR1A by text similarity (a relevance ranking, not an exhaustive list)

TrialPhaseStatus
The Effect of Allergen Immunotherapy on Anti-viral Immunity in Patients With Allergic Asthma PHASE4COMPLETED
Immunologic Basis of Anti-IgE Therapy (Study II: On Patients With Asthma) PHASE4COMPLETED
Prospective Double-blind Placebo-controlled Study of the Effect of Xolair (Omalizumab) in Chronic Urticaria Patients PHASE2/PHASE3COMPLETED
Allergic Rhinitis, Immunotherapy and Vitamin d PHASE2/PHASE3UNKNOWN
Chemotherapy Sequential Tislelizumab After Radical Resection in Patients With dMMR/MSI-H or POLE/POLD1 Mutations PHASE2NOT_YET_RECRUITING
Effect of Anti-IgE in Chronic Urticaria PHASE2COMPLETED
Safety and Efficacy Study of VIS649 for IgA Nephropathy PHASE2COMPLETED
Aerosol Combination Therapy of All-trans Retinoic Acid and Isotretinoin as A Novel Treatment for Inducing Neutralizing Antibodies in COVID -19 Infected Patients Better Than Vaccine : An Innovative Treatment PHASE2UNKNOWN
Post IVIG Medication in Children With Immune Thrombocytopenia PHASE1UNKNOWN
Lenalidomide and Dinutuximab With or Without Isotretinoin in Treating Younger Patients With Refractory or Recurrent Neuroblastoma PHASE1ACTIVE_NOT_RECRUITING
Preventive IVIG Therapy for Congenital Heart Block EARLY_PHASE1COMPLETED
Frequency of FCGR3A Gene Polymorphisms in Patients With Neuromyelitis Optica Spectrum Disorders, Anti-oligodendrocyte Myelin Protein Antibody Disease, and Multiple Sclerosis. nanRECRUITING
Prognostic Value of CD64 Marker for Patients in Intensive Care Unit nanUNKNOWN
Role of the Neonatal Fc Receptor for IgG in the Pathophysiology of Lupus nanCOMPLETED
Subclass of Donor-specific Antibody as a Risk Factor of Antibody Mediated Rejection in Renal Transplantation nanCOMPLETED
Study if the Presence of Functional FcERI/RII on the Surface of Human Blood Platelet nanUNKNOWN
Comparison Between Methyl Prednisolone and Intravenous Dexamethazone in Severe Immune Thrombocytopenic Purpra nanUNKNOWN
Kinetics of Nasal Cytokine Responses to Mechanical Stimulation nanCOMPLETED
Immune Response to Anti-HER2 Therapies in Patients With HER2-Positive Stage I-IV Breast Cancer nanRECRUITING
FGL2/Fibroleukin and Hepatitis C Virus Recurrence Post Liver Transplantation nanUNKNOWN
Does CMV Induced Changes in NK Lymphocyte Biology Influence the Effectiveness of Antibody Therapy Used to Treat B Cell Lymphoproliferative Diseases? nanUNKNOWN
Contribution of Nasal IgE Production to the Boost of Systemic Allergen-specific IgE Upon Nasal Allergen Contact nanRECRUITING
sCD163 & CD19 as Candidate Biomarkers in CIDP and MMN nanUNKNOWN
Correlation Between IgE Parameters and the Response to Omalizumab in Subjects With Severe Asthma nanWITHDRAWN
The Effect of Omalizumab on Responses to Cat Allergen Challenge nanCOMPLETED
Studying Blood and DNA Samples From Patients With Breast Cancer Treated With Chemotherapy With or Without Trastuzumab nanCOMPLETED
Applying Systems Immunology to the Search for Personalized Biomarkers of Clinical Efficacy nanCOMPLETED
Study of Neonatal IgG Fc Receptor Expression in Natural Killer T Cells Expressing an Invariant T Receptor : Implication in the Pathophysiology of Systemic Lupus nanRECRUITING
Cryoablation Combined With Cardonilizumab and Bevacizumab in Hepatocellular Carcinoma With Pulmonary Metastases nanRECRUITING
Obinutuzumab in the Management of Idiopathic Membranous Nephropathy nanUNKNOWN

Related proteins — ESM-2 sequence neighbours (a FCGR1A binder may also engage these)

ProteinNameSimilarity
Q92637 0.994 Q92637 →
P26151 0.992 P26151 →
E2RP87 0.992 E2RP87 →
P08637 0.991 P08637 →
Q68SN8 0.991 Q68SN8 →
Q09TM2 0.991 Q09TM2 →
Q8SPW2 0.991 Q8SPW2 →
Q9N2I5 0.990 Q9N2I5 →
A3RFZ7 0.990 A3RFZ7 →
Q09TM4 0.990 Q09TM4 →
P79107 0.988 P79107 →
H0VDZ8 0.987 H0VDZ8 →
P27645 0.987 P27645 →
M3XWH1 0.987 M3XWH1 →
FCGR3B Low affinity immunoglobulin gamma Fc region receptor III-B 0.986 landscape →
A0A0B4J1G0 0.986 A0A0B4J1G0 →
Q60513 0.985 Q60513 →
Q6DN72 0.985 Q6DN72 →
Q3B8P2 0.985 Q3B8P2 →
Q28942 0.984 Q28942 →
B6A8R8 0.984 B6A8R8 →
Q8SPV8 0.984 Q8SPV8 →
Q63203 0.984 Q63203 →
B6A8C7 0.984 B6A8C7 →
P08508 0.984 P08508 →
Q6XPU4 0.983 Q6XPU4 →
P08101 0.983 P08101 →
P0DTI4 0.982 P0DTI4 →
Q5NKV2 0.982 Q5NKV2 →
Q14953 0.982 Q14953 →