Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 11/20 | 0.46 |
| ▸ | F2 | P00734 | 2/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 4/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | TACR1 | P25103 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1385114 | 0.83 | F10 (0.49) | F10F2 | |
| SCHEMBL1385552 | 0.78 | F10 (0.54) | F10F2KDM4E | |
| SCHEMBL1385551 | 0.78 | F10 (0.54) | F10F2KDM4E | |
| SCHEMBL1385169 | 0.78 | F10 (0.41) | F10F2MAPT | |
| SCHEMBL1385962 | 0.76 | F10 (0.52) | F10F2KDM4E | |
| SCHEMBL1385601 | 0.76 | F10 (0.51) | F10F2 | |
| SCHEMBL1385600 | 0.76 | F10 (0.51) | F10F2 | |
| SCHEMBL1386136 | 0.75 | F10 (0.56) | F10F2KDM4E | |
| SCHEMBL1386737 | 0.75 | F10 (0.52) | F10F2KDM4E | |
| SCHEMBL1386675 | 0.74 | F10 (0.51) | F10F2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4829449-B2 | — | — | 2011-12-07 | — | — | JP | claimed |
| JP-2003508353-A | — | — | 2003-03-04 | — | — | JP | claimed |
| EP-1208097-A2 | SUBSTITUTED OXOAZAHETEROCYCLYL COMPOUNDS | Aventis Pharmaceuticals Inc. (US) | 2002-05-29 | — | — | EP | claimed |
| WO-2001007436-A2 | SUBSTITUTED OXOAZAHETEROCYCLYL COMPOUNDS | AVENTIS PHARMACEUTICALS INC. (US) | 2001-02-01 | — | — | WO | claimed |