Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 1/20 | 0.46 |
| ▸ | KDM1A | O60341 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.35 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.35 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.35 |
| ▸ | FAAH | O00519 | 1/20 | 0.35 |
| ▸ | CFTR | P13569 | 1/20 | 0.34 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.34 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.34 |
| ▸ | DOCK5 | Q9H7D0 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8039239 | 0.78 | TP53 (0.53) | KDM1AMAOAMAOBMAPT | |
| SCHEMBL8045006 | 0.70 | SLC6A4 (0.47) | SLC6A4CHRNB2CHRNA4 | |
| SCHEMBL13849999 | 0.69 | CHRNB2 (0.40) | SLC6A4KDM1AMAOAMAOBCHRNB2 | |
| SCHEMBL2135495 | 0.65 | SLC6A4 (0.52) | SLC6A4KDM1AMAOAMAOBCFTR | |
| SCHEMBL2135499 | 0.65 | SLC6A4 (0.52) | SLC6A4KDM1AMAOAMAOBCFTR | |
| SCHEMBL10288441 | 0.65 | SLC6A4 (0.52) | SLC6A4KDM1AMAOAMAOBCFTR | |
| SCHEMBL6354836 | 0.64 | CHRNA7 (0.55) | SLC6A4CHRM4 | |
| SCHEMBL10635883 | 0.64 | MAPT (0.43) | MAPTCHRM4 | |
| SCHEMBL731775 | 0.64 | MAPT (0.54) | MAPT | |
| SCHEMBL25005282 | 0.64 | SLC6A4 (0.57) | SLC6A4KDM1AMAOAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090118326-A1 | Nicotinic Acetylcholine Receptor Modulators | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2009-05-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090118326-A1 | Nicotinic Acetylcholine Receptor Modulators | CHRNA10, CHRNA6, CHRNA5 | SLC6A4 1198/4885KDM1A 519/4885MAOA 250/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.