Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 1/20 | 0.39 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.37 |
| ▸ | GRM2 | Q14416 | 3/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.35 |
| ▸ | CNR2 | P34972 | 4/20 | 0.35 |
| ▸ | CNR1 | P21554 | 3/20 | 0.35 |
| ▸ | PLA2G2A | P14555 | 2/20 | 0.35 |
| ▸ | HSP90B1 | P14625 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA7 | P43166 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13255534 | 0.93 | PDE3B (0.39) | CYP11B1CYP11B2MAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL13850837 | 0.92 | FFAR4 (0.45) | MAPTFFAR4GRM2HSP90AA1CNR2 | |
| SCHEMBL13850799 | 0.89 | MAPT (0.42) | MAPTFFAR4GRM2HSP90AA1CNR2 | |
| SCHEMBL13850757 | 0.88 | MAPT (0.43) | MAPTGRM2HSP90AA1CNR2CNR1 | |
| SCHEMBL13875850 | 0.87 | MAPT (0.41) | MAPTFFAR4GRM2HSP90AA1CNR2 | |
| SCHEMBL13875861 | 0.85 | MAPT (0.39) | MAPTFFAR4GRM2HSP90AA1CNR2 | |
| SCHEMBL13850797 | 0.85 | MAPT (0.39) | MAPTGRM2HSP90AA1CNR2CNR1 | |
| SCHEMBL13850809 | 0.85 | MAOB (0.41) | MAPTGRM2HSP90AA1ALDH1A1HPGD | |
| SCHEMBL13850749 | 0.85 | MAPT (0.43) | MAPTFFAR4GRM2CNR2CNR1 | |
| SCHEMBL13850804 | 0.85 | MAPT (0.39) | MAPTFFAR4GRM2HSP90AA1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090118233-A1 | Heterocyclic compounds having inhibitory activity against HIV integrase | MURAI HITOSHI | 2009-05-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090118233-A1 | Heterocyclic compounds having inhibitory activity against HIV integrase | CYP3A7, CDK7, CYP2A7 | CYP11B1 377/4885CYP11B2 736/4885MAPT 4308/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.