Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MYC | P01106 | 13/20 | 0.42 |
| ▸ | CTSB | P07858 | 2/20 | 0.42 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.42 |
| ▸ | ELANE | P08246 | 1/20 | 0.42 |
| ▸ | MMP9 | P14780 | 1/20 | 0.42 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.42 |
| ▸ | NR4A1 | P22736 | 5/20 | 0.41 |
| ▸ | HAAO | P46952 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.36 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3222862 | 0.81 | PDE4B (0.51) | PDE4BPDE3A | |
| SCHEMBL2968564 | 0.75 | PDE4B (0.46) | POLBKMT2AALDH1A1PDE4BPDE3A | |
| SCHEMBL13851030 | 0.72 | PDE4B (0.44) | POLBMAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL3460245 | 0.72 | DHODH (0.41) | MYCNR4A1TDP1POLBMAPT | |
| SCHEMBL2960864 | 0.70 | PDE4B (0.63) | PDE4BPDE3A | |
| SCHEMBL13851129 | 0.69 | PDE4B (0.46) | POLBMAPTPDE4BPDE3A | |
| SCHEMBL3221313 | 0.69 | PDE4B (0.64) | PDE4BPDE3A | |
| SCHEMBL3603220 | 0.65 | GABRP (0.56) | TDP1POLBMEN1KMT2AALDH1A1 | |
| SCHEMBL13851338 | 0.64 | KDM4E (0.44) | MYCNR4A1HAAOTDP1POLB | |
| SCHEMBL3222485 | 0.64 | DHODH (0.40) | MYCNR4A1TDP1RECQLALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2060572-A1 | PYRAZOLOPYRIDINE DERIVATIVE AND PHOSPHODIESTERASE (PDE) INHIBITOR CONTAINING THE SAME AS ACTIVE INGREDIENT | Kyorin Pharmaceutical Co., Ltd. (JP) | 2009-05-20 | — | — | EP | disclosed |