Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 5/20 | 0.65 |
| ▸ | THRA | P10827 | 2/20 | 0.53 |
| ▸ | THRB | P10828 | 2/20 | 0.53 |
| ▸ | FAAH | O00519 | 1/20 | 0.43 |
| ▸ | PLA2G2D | Q9UNK4 | 1/20 | 0.43 |
| ▸ | PPARG | P37231 | 1/20 | 0.43 |
| ▸ | PPARA | Q07869 | 1/20 | 0.43 |
| ▸ | RXRA | P19793 | 1/20 | 0.42 |
| ▸ | RXRB | P28702 | 1/20 | 0.42 |
| ▸ | RXRG | P48443 | 1/20 | 0.42 |
| ▸ | S1PR4 | O95977 | 2/20 | 0.41 |
| ▸ | S1PR5 | Q9H228 | 2/20 | 0.41 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.41 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.41 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12337602 | 0.86 | S1PR1 (0.71) | S1PR1THRATHRBPLA2G2DRXRA | |
| SCHEMBL13851992 | 0.85 | S1PR1 (0.71) | S1PR1THRATHRBPLA2G2DS1PR4 | |
| SCHEMBL13665426 | 0.83 | S1PR1 (0.65) | S1PR1THRATHRBPLA2G2DRXRA | |
| SCHEMBL12337248 | 0.82 | S1PR1 (0.83) | S1PR1THRATHRBS1PR4S1PR5 | |
| SCHEMBL2463211 | 0.80 | S1PR1 (0.63) | S1PR1THRATHRBPLA2G2DPPARG | |
| SCHEMBL2468704 | 0.80 | S1PR1 (0.70) | S1PR1THRATHRBPLA2G2DRXRA | |
| SCHEMBL13665201 | 0.80 | S1PR1 (0.63) | S1PR1THRATHRBPLA2G2DPPARG | |
| SCHEMBL10280847 | 0.79 | S1PR1 (0.59) | S1PR1THRATHRBPPARGPPARA | |
| Amiselimod SCHEMBL2463680 | 0.79 | S1PR1 (1.00) | S1PR1THRATHRBS1PR4S1PR5 | |
| SCHEMBL12336974 | 0.79 | S1PR1 (1.00) | S1PR1THRATHRBS1PR4S1PR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090137530-A1 | Amine Compound and Use Thereof for Medical Purposes | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2009-05-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090137530-A1 | Amine Compound and Use Thereof for Medical Purposes | HRH3, HRH2, HRH4 | S1PR1 370/4885THRA 705/4885THRB 536/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.