Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 1/20 | 0.37 |
| ▸ | RRM2 | P31350 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18517598 | 0.83 | IDO1 (0.42) | CCR1RRM2ALDH1A1POLB | |
| SCHEMBL12401951 | 0.80 | IRAK4 (0.37) | CCR1ALDH1A1POLB | |
| SCHEMBL2279175 | 0.75 | MAPK14 (0.36) | CCR1ALDH1A1POLB | |
| SCHEMBL31003229 | 0.74 | CCR1 (0.41) | CCR1ALDH1A1POLB | |
| SCHEMBL9256292 | 0.74 | CCR1 (0.41) | CCR1ALDH1A1POLB | |
| SCHEMBL18517575 | 0.74 | CCR1 (0.41) | CCR1RRM2ALDH1A1 | |
| SCHEMBL17901890 | 0.70 | CCR1 (0.37) | CCR1ALDH1A1 | |
| SCHEMBL12402766 | 0.68 | HSD17B1 (0.31) | ALDH1A1 | |
| SCHEMBL22298536 | 0.60 | MGAM (0.37) | ALDH1A1 | |
| SCHEMBL21018542 | 0.60 | CCR1 (0.50) | CCR1RRM2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090118272-A1 | BENZOTHIAZOLE AND AZABENZOTHIAZOLE COMPOUNDS USEFUL AS KINASE INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY | 2009-05-07 | — | — | US | disclosed |
| US-7473784-B2 | Benzothiazole and azabenzothiazole compounds useful as kinase inhibitors | BRISTOL-MYERS SQUIBB COMPANY (US) | 2009-01-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090118272-A1 | BENZOTHIAZOLE AND AZABENZOTHIAZOLE COMPOUNDS USEFUL AS KINASE INHIBITORS | GRK2, MAPK9, MAPK1 | CCR1 2351/4885RRM2 949/4885ALDH1A1 2753/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.