SCHEMBL13855070

SCHEMBL13855070

CCOC(=O)CNC(=O)Nc1ccc(/C(N)=N/C(=O)OC(C)(C)C)cc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ PPID Q08752 3/20 0.46
▸ HDAC1 Q13547 2/20 0.45
▸ HDAC2 Q92769 2/20 0.45
▸ MAPT P10636 4/20 0.43
▸ KDM4E B2RXH2 2/20 0.43
▸ NAMPT P43490 2/20 0.41
▸ ALDH1A1 P00352 2/20 0.41
▸ HTT P42858 1/20 0.41
▸ CA12 O43570 1/20 0.41
▸ CA1 P00915 1/20 0.41
▸ CA2 P00918 1/20 0.41
▸ CA9 Q16790 1/20 0.41
▸ NPC1 O15118 1/20 0.41
▸ RAB9A P51151 1/20 0.41
▸ PPIB P23284 1/20 0.41
▸ PPIA P62937 1/20 0.41
▸ PPIG Q13427 1/20 0.41
▸ TSHR P16473 1/20 0.41
▸ LMNA P02545 1/20 0.41
▸ SMN1; SMN2 Q16637 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13855069 0.87 HDAC1 (0.44) HDAC1HDAC2ALDH1A1CA12CA1
SCHEMBL10456811 0.81 PPID (0.56) PPIDMAPTKDM4ENAMPTALDH1A1
SCHEMBL13855068 0.79 F7 (0.47) HDAC1HDAC2F7
SCHEMBL4414766 0.78 F7 (0.57) PPIDF7
SCHEMBL13855055 0.77 SMN1; SMN2 (0.42) MAPTNAMPTALDH1A1NPC1RAB9A
SCHEMBL8910810 0.77 L3MBTL1 (0.48) PPIDMAPTKDM4ENAMPTALDH1A1
SCHEMBL4417206 0.76 PPID (0.47) PPIDMAPTKDM4ENAMPTALDH1A1
SCHEMBL13855054 0.76 SMN1; SMN2 (0.43) MAPTNAMPTALDH1A1NPC1RAB9A
SCHEMBL10458385 0.76 CA12 (0.50) HDAC1HDAC2MAPTKDM4EALDH1A1
SCHEMBL10192183 0.75 PPID (0.62) PPIDMAPTKDM4EALDH1A1HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090130085-A1 Amidino-Compounds for Stabilizing Factor VII Polypeptide Formulations NOVO NORDISH HEALTHCARE AG (CH) 2009-05-21 — — US disclosed
US-20090130085-A1 Amidino-Compounds for Stabilizing Factor VII Polypeptide Formulations NOVO NORDISH HEALTHCARE AG (CH) 2009-05-21 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090130085-A1 Amidino-Compounds for Stabilizing Factor VII Polypeptide Formulations F7, F5, F8 PPID 417/4885HDAC1 3155/4885HDAC2 4308/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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