Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 16/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.68 |
| ▸ | MEN1 | O00255 | 6/20 | 0.68 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.68 |
| ▸ | RAB9A | P51151 | 3/20 | 0.68 |
| ▸ | NPC1 | O15118 | 4/20 | 0.60 |
| ▸ | GAA | P10253 | 2/20 | 0.60 |
| ▸ | POLB | P06746 | 2/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.60 |
| ▸ | APP | P05067 | 1/20 | 0.60 |
| ▸ | THRB | P10828 | 1/20 | 0.60 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.60 |
| ▸ | CASP1 | P29466 | 1/20 | 0.60 |
| ▸ | SNCA | P37840 | 1/20 | 0.60 |
| ▸ | CASP7 | P55210 | 1/20 | 0.60 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.60 |
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | TP53 | P04637 | 4/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13857585 | 0.85 | MAPT (0.73) | MAPTKMT2AMEN1KDM4ERAB9A | |
| SCHEMBL12157507 | 0.85 | MAPT (0.68) | MAPTKMT2AMEN1KDM4ERAB9A | |
| SCHEMBL5339968 | 0.83 | MAPT (0.77) | MAPTKMT2AMEN1KDM4ERAB9A | |
| SCHEMBL2246115 | 0.81 | MAPT (1.00) | MAPTKMT2AMEN1KDM4ERAB9A | |
| SCHEMBL34465504 | 0.80 | MAPT (0.64) | MAPTKMT2AMEN1KDM4ERAB9A | |
| SCHEMBL7059138 | 0.80 | MAPT (0.64) | MAPTKMT2AMEN1KDM4ERAB9A | |
| SCHEMBL5259019 | 0.79 | MAPT (0.64) | MAPTKMT2AMEN1KDM4ERAB9A | |
| SCHEMBL15958900 | 0.79 | MAPT (0.64) | MAPTKMT2AMEN1KDM4ERAB9A | |
| SCHEMBL2790890 | 0.78 | MAPT (0.69) | MAPTKMT2AMEN1KDM4ERAB9A | |
| SCHEMBL3591227 | 0.78 | MAPT (0.69) | MAPTKMT2AMEN1KDM4ERAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009061755-A1 | ORGANIC FLUORESCENT COMPOSITIONS | HONEYWELL INTERNATIONAL INC. (US) | 2009-05-14 | — | — | WO | disclosed |